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Uba5
Gene Detail
 Symbol
Name
ID
Uba5
ubiquitin-like modifier activating enzyme 5
MGI:1913913
Synonyms 5730525G14Rik, Ube1dc1
Feature Type protein coding gene
Genetic Map
Chromosome 9
56.28 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:104046599-104063134 bp, - strand
From VEGA annotation of GRCm38

  16536 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11738  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Uba5

Human
homologs
Human Homolog UBA5, ubiquitin-like modifier activating enzyme 5
NCBI Gene ID 79876
neXtProt AC  NX_Q9GZZ9
Human Synonyms  THIFP1, UBE1DC1
Human Chr (Location)  3q22.1; chr3:132654446-132678623 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele die at E12.5.
 
Interactions
Uba5 interacts with 172 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process oxidation-reduction process, protein ufmylation, ...
Component cytoplasm, cytosol, ...
Function ATP binding, catalytic activity, ...
External Resources: FuncBase
Expression
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000027430 (Evidence)
Ensembl Gene ModelENSMUSG00000032557 (Evidence)
Entrez Gene66663 (Evidence)
DoTSDT.101385858, DT.50317278, DT.60103100, DT.94269298
NIA Mouse Gene IndexU031266, U031267
Consensus CDS ProjectCCDS23457.1
International Mouse Knockout Project StatusUba5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027430 VEGA Gene Model | MGI Sequence Detail 16536 C57BL/6J ±  kb
transcript OTTMUST00000067872 VEGA | MGI Sequence Detail 2404 Not Applicable 
polypeptide OTTMUSP00000034217 VEGA | MGI Sequence Detail 403 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(5) UniProt(3)
Polymorphisms SNPs within 2kb(169 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
InterPro IPR009036 Molybdenum cofactor biosynthesis, MoeB
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR000594 UBA/THIF-type NAD/FAD binding fold
Protein Ontology PR:000016953 ubiquitin-like modifier-activating enzyme 5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:195351 Zhang Y, et al., Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking. PLoS One. 2012;7(11):e48587
All references(31)
Other
accession IDs
MGI:2143304

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory