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Uba5
Gene Detail
Symbol

Name
ID
Uba5
ubiquitin-like modifier activating enzyme 5
MGI:1913913
Synonyms
5730525G14Rik, Ube1dc1
Feature Type
protein coding gene
Genetic Map
Chromosome 9
56.28 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:104046599-104063134 bp, - strand
From VEGA annotation of GRCm38

  16536 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11738  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: UBA5
Gene Tree: Uba5

Human
homologs
UBA5, ubiquitin-like modifier activating enzyme 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 79876
neXtProt AC: NX_Q9GZZ9

Human Synonyms: THIFP1, UBE1DC1

Human Chr (Location): 3q22.1; chr3:132654446-132678253 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele die at E12.5.
 
Interactions
Uba5 interacts with 172 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process protein K69-linked ufmylation, protein ufmylation, ...
Component cytoplasm, cytosol, ...
Function ATP binding, metal ion binding, ...
External Resources: FuncBase
Expression
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase uba5 ; ZFIN uba5    NEW 
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000027430 (Evidence)
Ensembl Gene Model ENSMUSG00000032557 (Evidence)
Entrez Gene 66663 (Evidence)
DoTS DT.94269298, DT.60103100, DT.101385858, DT.50317278
NIA Mouse Gene Index U031267, U031266
Consensus CDS Project CCDS23457.1
International Mouse Phenotyping Consortium Status Uba5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027430 VEGA Gene Model | MGI Sequence Detail 16536 C57BL/6J ±  kb
transcript OTTMUST00000067872 VEGA | MGI Sequence Detail 2404 Not Applicable 
polypeptide OTTMUSP00000034217 VEGA | MGI Sequence Detail 403 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(169 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009036 Molybdenum cofactor biosynthesis, MoeB
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR000594 UBA/THIF-type NAD/FAD binding fold
Protein Ontology PR:000016953 ubiquitin-like modifier-activating enzyme 5
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:195351 Zhang Y, et al., Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking. PLoS One. 2012;7(11):e48587
All references(30)
Other
accession IDs
MGI:2143304

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory