About   Help   FAQ
Eef1d Gene Detail
Summary
  • Symbol
    Eef1d
  • Name
    eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
  • Synonyms
    1700026P12Rik, 5730529A16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913906
    NCBI Gene: 66656
  • Gene Overview
    MyGene.info: EEF1D
Location & Maps
more
  • Sequence Map
    Chr15:75894796-75909556 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14761 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 35.05 cM, cytoband E1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EEF1D, eukaryotic translation elongation factor 1 delta
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EEF1D, eukaryotic translation elongation factor 1 delta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EF1D, EF-1D, FP1047
  • Links
    NCBI Gene ID: 1936
    neXtProt AC: NX_P29692

  • Chr Location
    8q24.3; chr8:143579697-143597675 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 23404
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EEF1D
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
  • All Mutations and Alleles
    33
  • Chemically induced (other)
    3
  • Gene trapped
    26
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    5 involving Eef1d
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019797 VEGA Gene Model | MGI Sequence Detail 14761 C57BL/6J ±  kb
transcript OTTMUST00000047339 VEGA | MGI Sequence Detail 2152 Not Applicable  
polypeptide OTTMUSP00000021367 VEGA | MGI Sequence Detail 660 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    43 from dbSNP Build 142
Protein
Information
less
  • UniProt
    15 Sequences
  • InterPro Domains
    IPR018940 Elongation factor 1 beta central acidic region, eukaryote
    IPR001326 Translation elongation factor EF1B, beta/delta chains, conserved site
    IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain
    IPR014717 Translation elongation factor EF1B/ribosomal protein S6
Molecular
Reagents
less
  • All nucleic 214
    cDNA 214

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923826, MGI:2144348
References
more
  • Summaries
    All 34
    Diseases 1
    Gene Ontology 4
    Phenotypes 30
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:217985 Kaitsuka T, et al., Transformation of eEF1Bdelta into heat-shock response transcription factor by alternative splicing. EMBO Rep. 2011 Jul;12(7):673-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/22/2016
MGI 6.06
The Jackson Laboratory