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Ctnnbl1 Gene Detail
Summary
  • Symbol
    Ctnnbl1
  • Name
    catenin, beta like 1
  • Synonyms
    5730471K09Rik, FLJ21108, NYD-SP19, P14L
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913892
    NCBI Gene: 66642
  • Gene Overview
    MyGene.info: CTNNBL1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:157737401-157891614 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 78.40 cM, cytoband H2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    813 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913892
protein coding gene Chr2:157737401-157891903 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026785
protein coding gene Chr2:162761181-162923377 (+)
A/J MGP_AJ_G0026751
protein coding gene Chr2:156243938-156402608 (+)
AKR/J MGP_AKRJ_G0026722
protein coding gene Chr2:160864723-161022953 (+)
BALB/cJ MGP_BALBcJ_G0026760
protein coding gene Chr2:156554322-156707495 (+)
C3H/HeJ MGP_C3HHeJ_G0026502
protein coding gene Chr2:161164314-161324348 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027209
protein coding gene Chr2:167609156-167769216 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024579
protein coding gene Chr2:149689902-149849321 (+)
CAST/EiJ MGP_CASTEiJ_G0025964
protein coding gene Chr2:161523817-161684285 (+)
CBA/J MGP_CBAJ_G0026479
protein coding gene Chr2:173635221-173796547 (+)
DBA/2J MGP_DBA2J_G0026617
protein coding gene Chr2:155427154-155581230 (+)
FVB/NJ MGP_FVBNJ_G0026584
protein coding gene Chr2:153826034-153980974 (+)
LP/J MGP_LPJ_G0026720
protein coding gene Chr2:162850896-163011917 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026605
protein coding gene Chr2:177472648-177629818 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027265
protein coding gene Chr2:160670851-160830266 (+)
PWK/PhJ MGP_PWKPhJ_G0025698
protein coding gene Chr2:154941797-155097875 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025501
protein coding gene Chr2:159600974-159760957 (+)
WSB/EiJ MGP_WSBEiJ_G0026034
protein coding gene Chr2:161567246-161729938 (+)



Homology
more
  • Human Ortholog
    CTNNBL1, catenin beta like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CTNNBL1, catenin beta like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf33, dJ633O20.1, NAP, P14L, PP8304
  • Links
    NCBI Gene ID: 56259
    neXtProt AC: NX_Q8WYA6
    UniProt: Q8WYA6

  • Chr Location
    20q11.23; chr20:37693955-37872129 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 4 alleles in 3 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027649 Ensembl Gene Model | MGI Sequence Detail 154214 C57BL/6J ±  kb
transcript ENSMUST00000029178 Ensembl | MGI Sequence Detail 2442 Not Applicable  
polypeptide ENSMUSP00000029178 Ensembl | MGI Sequence Detail 563 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR013180 Beta-catenin-like protein 1, N-terminal
Molecular
Reagents
less
  • All nucleic 73
    cDNA 73

    Microarray probesets 5
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:45934 Korinek V, et al., Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. Mol Cell Biol. 1998 Mar;18(3):1248-56
  • Latest
    J:232010 Chandra A, et al., Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice. Cell Cycle. 2013 Mar 1;12(5):732-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory