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Tsen15 Gene Detail
Summary
  • Symbol
    Tsen15
  • Name
    tRNA splicing endonuclease subunit 15
  • Synonyms
    5730449L18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913887
    NCBI Gene: 66637
  • Gene Overview
    MyGene.info: TSEN15
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:152370735-152386682 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 64.75 cM, cytoband G2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    250 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913887
protein coding gene Chr1:152370735-152386688 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016586
protein coding gene Chr1:157136245-157151741 (-)
A/J MGP_AJ_G0016568
protein coding gene Chr1:150798742-150814582 (-)
AKR/J MGP_AKRJ_G0016533
protein coding gene Chr1:155454078-155474330 (-)
BALB/cJ MGP_BALBcJ_G0016528
protein coding gene Chr1:151374440-151390941 (-)
C3H/HeJ MGP_C3HHeJ_G0016353
protein coding gene Chr1:155564684-155587903 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016989
protein coding gene Chr1:162571212-162588937 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014698
protein coding gene Chr1:143121630-143136533 (-)
CAST/EiJ MGP_CASTEiJ_G0015932
protein coding gene Chr1:155053408-155072464 (-)
CBA/J MGP_CBAJ_G0016327
protein coding gene Chr1:168288856-168309646 (-)
DBA/2J MGP_DBA2J_G0016433
protein coding gene Chr1:149828209-149844308 (-)
FVB/NJ MGP_FVBNJ_G0016431
protein coding gene Chr1:148299828-148315354 (-)
LP/J MGP_LPJ_G0016504
protein coding gene Chr1:158235023-158255398 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016457
protein coding gene Chr1:175944000-175975605 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017025
protein coding gene Chr1:155235244-155251192 (-)
PWK/PhJ MGP_PWKPhJ_G0015718
protein coding gene Chr1:148823247-148839381 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015505
protein coding gene Chr1:154053627-154071289 (-)
WSB/EiJ MGP_WSBEiJ_G0015995
protein coding gene Chr1:155297636-155315134 (-)



Homology
more
  • Human Ortholog
    TSEN15, tRNA splicing endonuclease subunit 15
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TSEN15, tRNA splicing endonuclease subunit 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf19, PCH2F, sen15
  • Links
    NCBI Gene ID: 116461
    neXtProt AC: NX_Q8WW01
    UniProt: Q8WW01

  • Chr Location
    1q25.3; chr1:184050207-184095846 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66637 NCBI Gene Model | MGI Sequence Detail 15948 C57BL/6J ±  kb
transcript NM_025677 RefSeq | MGI Sequence Detail 1147 C57BL/6  
polypeptide Q8R3W5 UniProt | EBI | MGI Sequence Detail 168 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR011856 tRNA endonuclease-like domain superfamily
    IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily
    IPR018593 tRNA-splicing endonuclease subunit Sen15
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory