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Ntmt1 Gene Detail
Summary
  • Symbol
    Ntmt1
  • Name
    N-terminal Xaa-Pro-Lys N-methyltransferase 1
  • Synonyms
    2610205E22Rik, Mettl11a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913867
    NCBI Gene: 66617
Location & Maps
more
  • Sequence Map
    Chr2:30807826-30823033 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15208 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 21.74 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NTMT1, N-terminal Xaa-Pro-Lys N-methyltransferase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NTMT1, N-terminal Xaa-Pro-Lys N-methyltransferase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NTM1A
  • Links
    NCBI Gene ID: 28989
    neXtProt AC: NX_Q9BV86

  • Chr Location
    9q34.11; chr9:129608884-129636131 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    36
  • Gene trapped
    33
  • Targeted
    3
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011871 VEGA Gene Model | MGI Sequence Detail 15208 C57BL/6J ±  kb
transcript OTTMUST00000027955 VEGA | MGI Sequence Detail 1387 Not Applicable  
polypeptide OTTMUSP00000012686 VEGA | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    119 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000010343 methyltransferase-like protein 11A
  • EC
  • InterPro Domains
    IPR008576 Alpha-N-methyltransferase NTM1
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
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  • All nucleic 52
    cDNA 52

    Microarray probesets 5
Other
Accession IDs
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MGI:2139140, MGI:2145326
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:206007 Petkowski JJ, et al., NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1. Biochem J. 2013 Dec 15;456(3):453-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory