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Lrrc57 Gene Detail
Summary
  • Symbol
    Lrrc57
  • Name
    leucine rich repeat containing 57
  • Synonyms
    2810002D13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913856
    NCBI Gene: 66606
  • Gene Overview
    MyGene.info: LRRC57
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120604238-120609508 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913856
protein coding gene Chr2:120604238-120609520 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026370
protein coding gene Chr2:123471808-123477099 (-)
A/J MGP_AJ_G0026331
protein coding gene Chr2:118421860-118427141 (-)
AKR/J MGP_AKRJ_G0026310
protein coding gene Chr2:121725963-121731254 (-)
BALB/cJ MGP_BALBcJ_G0026344
protein coding gene Chr2:118658773-118664054 (-)
C3H/HeJ MGP_C3HHeJ_G0026090
protein coding gene Chr2:122217100-122222391 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026791
protein coding gene Chr2:127500025-127505307 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024171
protein coding gene Chr2:113436446-113441721 (-)
CAST/EiJ MGP_CASTEiJ_G0025552
protein coding gene Chr2:122519393-122524685 (-)
CBA/J MGP_CBAJ_G0026066
protein coding gene Chr2:131962561-131967852 (-)
DBA/2J MGP_DBA2J_G0026205
protein coding gene Chr2:117813691-117818972 (-)
FVB/NJ MGP_FVBNJ_G0026167
protein coding gene Chr2:116646480-116651771 (-)
LP/J MGP_LPJ_G0026306
protein coding gene Chr2:123737640-123742931 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026186
protein coding gene Chr2:136271083-136276374 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026846
protein coding gene Chr2:121856678-121861969 (-)
PWK/PhJ MGP_PWKPhJ_G0025288
protein coding gene Chr2:117415887-117421246 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025087
protein coding gene Chr2:121060805-121066098 (-)
WSB/EiJ MGP_WSBEiJ_G0025621
protein coding gene Chr2:122686301-122691593 (-)



Homology
more
  • Human Ortholog
    LRRC57, leucine rich repeat containing 57
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LRRC57, leucine rich repeat containing 57
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 255252
    neXtProt AC: NX_Q8N9N7
    UniProt: Q8N9N7

  • Chr Location
    15q15.2; chr15:42528332-42548804 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11995
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LRRC57
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Lrrc57
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66606 NCBI Gene Model | MGI Sequence Detail 5271 C57BL/6J ±  kb
transcript NM_001159612 RefSeq | MGI Sequence Detail 1982 C57BL/6  
polypeptide Q9D1G5 UniProt | EBI | MGI Sequence Detail 239 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR025875 Leucine rich repeat 4
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
less
  • All nucleic 48
    cDNA 48

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138742
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory