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Farsa
Gene Detail
 Symbol
Name
ID
Farsa
phenylalanyl-tRNA synthetase, alpha subunit
MGI:1913840
Synonyms 0610012A19Rik, Farsla
Feature Type protein coding gene
Genetic Map
Chromosome 8
41.23 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:84856989-84869257 bp, + strand
From VEGA annotation of GRCm38

  12269 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3280  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: cytosolic phenylalanine-tRNA ligase beta chain
Gene Tree: Farsa

Human
homologs
Human Homolog FARSA, phenylalanyl-tRNA synthetase, alpha subunit
NCBI Gene ID 2193
neXtProt AC  NX_Q9Y285
Human Synonyms  CML33, FARSL, FARSLA, FRSA, PheHA
Human Chr (Location)  19p13.2; chr19:12922470-12933744 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(18) : Gene trapped(16) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Farsa interacts with 189 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process phenylalanyl-tRNA aminoacylation, translation, ...
Component cytoplasm, membrane
Function aminoacyl-tRNA ligase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (146)    Tissues (102)    Images (30)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 146
cDNA source data(116)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(116) cDNA(116)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000022260 (Evidence)
Ensembl Gene ModelENSMUSG00000003808 (Evidence)
Entrez Gene66590 (Evidence)
UniGene292517
DFCITC1572424, TC1586416, TC1680426
DoTSDT.101402342, DT.101719889, DT.110903276, DT.110903277, DT.491343, DT.55167666, DT.94286063
EC6.1.1.20
Consensus CDS ProjectCCDS22480.2
International Mouse Knockout Project StatusFarsa
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022260 VEGA Gene Model | MGI Sequence Detail 12269 C57BL/6J ±  kb
transcript OTTMUST00000052994 VEGA | MGI Sequence Detail 1826 Not Applicable 
polypeptide OTTMUSP00000025176 VEGA | MGI Sequence Detail 508 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(5) UniProt(7)
Polymorphisms SNPs within 2kb(97 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006195 Aminoacyl-tRNA synthetase, class II
InterPro IPR013196 Helix-turn-helix, type 11
InterPro IPR002319 Phenylalanyl-tRNA synthetase
InterPro IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000007346 phenylalanine--tRNA ligase alpha subunit
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory