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Exosc1 Gene Detail
Summary
  • Symbol
    Exosc1
  • Name
    exosome component 1
  • Synonyms
    2610035C18Rik, 2610104C07Rik, 2610312F07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913833
    NCBI Gene: 66583
  • Gene Overview
    MyGene.info: EXOSC1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:41922980-41933314 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 35.46 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    142 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913833
protein coding gene Chr19:41922978-41933403 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025131
protein coding gene Chr19:41226522-41236631 (-)
A/J MGP_AJ_G0025108
protein coding gene Chr19:39244032-39254398 (-)
AKR/J MGP_AKRJ_G0025076
protein coding gene Chr19:40533862-40543977 (-)
BALB/cJ MGP_BALBcJ_G0025102
protein coding gene Chr19:39302924-39313289 (-)
C3H/HeJ MGP_C3HHeJ_G0024862
protein coding gene Chr19:40683876-40693992 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025545
protein coding gene Chr19:42301109-42311479 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022959
protein coding gene Chr19:38599599-38608487 (-)
CAST/EiJ MGP_CASTEiJ_G0024327
protein coding gene Chr19:40355063-40364955 (-)
CBA/J MGP_CBAJ_G0024842
protein coding gene Chr19:44363557-44373673 (-)
DBA/2J MGP_DBA2J_G0024974
protein coding gene Chr19:39094759-39104870 (-)
FVB/NJ MGP_FVBNJ_G0024935
protein coding gene Chr19:38868409-38879536 (-)
LP/J MGP_LPJ_G0025060
protein coding gene Chr19:41220537-41230686 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024966
protein coding gene Chr19:43989262-44000678 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025603
protein coding gene Chr19:40571509-40581622 (-)
PWK/PhJ MGP_PWKPhJ_G0024076
protein coding gene Chr19:38969384-38979721 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023880
protein coding gene Chr19:39315553-39326051 (-)
WSB/EiJ MGP_WSBEiJ_G0024397
protein coding gene Chr19:40725368-40735488 (-)



Homology
more
  • Human Ortholog
    EXOSC1, exosome component 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EXOSC1, exosome component 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-108, CSL4, Csl4p, p13, SKI4, Ski4p
  • Links
    NCBI Gene ID: 51013
    neXtProt AC: NX_Q9Y3B2
    UniProt: Q9Y3B2

  • Chr Location
    10q24.1; chr10:97435909-97446065 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034321 Ensembl Gene Model | MGI Sequence Detail 10335 C57BL/6J ±  kb
transcript ENSMUST00000075280 Ensembl | MGI Sequence Detail 1622 Not Applicable  
polypeptide ENSMUSP00000074756 Ensembl | MGI Sequence Detail 195 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 51
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1913871, MGI:1914932, MGI:2147537
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:247257 Wolf I, et al., cDNA-library testing identifies transforming genes cooperating with c-myc in mouse pre-B cells. Eur J Immunol. 2016 Nov;46(11):2555-2565

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory