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Exosc1 Gene Detail
Summary
  • Symbol
    Exosc1
  • Name
    exosome component 1
  • Synonyms
    2610035C18Rik, 2610104C07Rik, 2610312F07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913833
    NCBI Gene: 66583
  • Gene Overview
    MyGene.info: EXOSC1
Location & Maps
more
  • Sequence Map
    Chr19:41922980-41933314 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10335 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 35.46 cM, cytoband D1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    EXOSC1, exosome component 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EXOSC1, exosome component 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-108, CSL4, Csl4p, p13, SKI4, Ski4p
  • Links
    NCBI Gene ID: 51013
    neXtProt AC: NX_Q9Y3B2

  • Chr Location
    10q24.1; chr10:97435909-97446011 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    12
  • Gene trapped
    10
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034321 Ensembl Gene Model | MGI Sequence Detail 10335 C57BL/6J ±  kb
transcript ENSMUST00000075280 Ensembl | MGI Sequence Detail 1622 Not Applicable  
polypeptide ENSMUSP00000074756 Ensembl | MGI Sequence Detail 195 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    142 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 6
Other
Accession IDs
less
MGI:1913871, MGI:1914932, MGI:2147537
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:185743 Cotney J, et al., Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb. Genome Res. 2012 Jun;22(6):1069-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory