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Aggf1
Gene Detail
Symbol

Name
ID
Aggf1
angiogenic factor with G patch and FHA domains 1
MGI:1913799
Synonyms
2010009L17Rik, 2310029P06Rik, VG5Q
Feature Type
protein coding gene
Genetic Map
Chromosome 13
49.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:95350683-95375352 bp, - strand
From VEGA annotation of GRCm38

  24670 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41220  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: AGGF1
Gene Tree: Aggf1

Human
homologs
AGGF1, angiogenic factor with G patch and FHA domains 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 55109
neXtProt AC: NX_Q8N302

Human Synonyms: GPATC7, GPATCH7, HSU84971, HUS84971, VG5Q

Human Chr (Location): 5q13.3; chr5:77030385-77065234 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(5) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Aggf1 interacts with 154 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process angiogenesis, cell adhesion, ...
Component cytoplasm, extracellular region, ...
Function nucleic acid binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (49)    Tissues (48)    Images (11)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 47
RT-PCR 2
cDNA source data(112)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase aggf1 ; ZFIN aggf1    NEW 
Molecular
reagents
All nucleic(113) cDNA(112) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000030737 (Evidence)
Ensembl Gene Model ENSMUSG00000021681 (Evidence)
Entrez Gene 66549 (Evidence)
UniGene 36785
DFCI TC1652651, TC1576684
DoTS DT.91447545, DT.492654, DT.99867960
NIA Mouse Gene Index U035052
Consensus CDS Project CCDS26697.1
International Mouse Phenotyping Consortium Status Aggf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030737 VEGA Gene Model | MGI Sequence Detail 24670 C57BL/6J ±  kb
transcript OTTMUST00000076097 VEGA | MGI Sequence Detail 3249 Not Applicable 
polypeptide OTTMUSP00000040000 VEGA | MGI Sequence Detail 711 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(141 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000253 Forkhead-associated (FHA) domain
InterPro IPR000467 G-patch domain
InterPro IPR008984 SMAD/FHA domain
Protein Ontology PR:000003830 angiogenic factor with G patch and FHA domains 1
References
(Earliest) J:28008 Harrison SM, et al., Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Development. 1995 Aug;121(8):2479-89
(Latest) J:154247 Mueller CF, et al., The heterogenous nuclear riboprotein S1-1 regulates AT1 receptor gene expression via transcriptional and posttranscriptional mechanisms. Arch Biochem Biophys. 2009 Aug 1;488(1):76-82
All references(34)
Other
accession IDs
MGI:2145413, MGI:2447861

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory