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Adamtsl5 Gene Detail
Summary
  • Symbol
    Adamtsl5
  • Name
    ADAMTS-like 5
  • Synonyms
    2010109H09Rik, Thsd6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913798
    NCBI Gene: 66548
Location & Maps
more
  • Sequence Map
    Chr10:80339110-80348412 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9303 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ADAMTSL5, ADAMTS like 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ADAMTSL5, ADAMTS like 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    THSD6
  • Links
    NCBI Gene ID: 339366
    neXtProt AC: NX_Q6ZMM2

  • Chr Location
    19p13.3; chr19:1505018-1513189 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Adamtsl5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019127 VEGA Gene Model | MGI Sequence Detail 9303 C57BL/6J ±  kb
transcript OTTMUST00000045832 VEGA | MGI Sequence Detail 1957 Not Applicable  
polypeptide OTTMUSP00000020648 VEGA | MGI Sequence Detail 485 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    8 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:192744 Bader HL, et al., A disintegrin-like and metalloprotease domain containing thrombospondin type 1 motif-like 5 (ADAMTSL5) is a novel fibrillin-1-, fibrillin-2-, and heparin-binding member of the ADAMTS superfamily containing a netrin-like module. Matrix Biol. 2012 Sep-Oct;31(7-8):398-411

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory