About   Help   FAQ
Fam107b Gene Detail
Summary
  • Symbol
    Fam107b
  • Name
    family with sequence similarity 107, member B
  • Synonyms
    3110001A13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913790
    NCBI Gene: 66540
  • Alliance
    gene page
  • Transcription Start Sites
    26 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:3571525-3783179 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, Syntenic
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5536 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913790
 protein coding gene Chr2:3571484-3783179 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025312
 protein coding gene Chr2:617502-803413 (+)
A/J MGP_AJ_G0025289
 protein coding gene Chr2:564069-738684 (+)
AKR/J MGP_AKRJ_G0025257
 protein coding gene Chr2:579573-754597 (+)
BALB/cJ MGP_BALBcJ_G0025285
 protein coding gene Chr2:549905-725460 (+)
C3H/HeJ MGP_C3HHeJ_G0025045
 protein coding gene Chr2:593010-768899 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025727
 protein coding gene Chr2:603837-786462 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023141
 protein coding gene Chr2:492752-659342 (+)
CAST/EiJ MGP_CASTEiJ_G0024508
 protein coding gene Chr2:592000-770337 (+)
CBA/J MGP_CBAJ_G0025024
 protein coding gene Chr2:644182-830933 (+)
DBA/2J MGP_DBA2J_G0025156
 protein coding gene Chr2:646450-714765 (+)
FVB/NJ MGP_FVBNJ_G0025118
 protein coding gene Chr2:558064-731210 (+)
LP/J MGP_LPJ_G0025242
 protein coding gene Chr2:603105-792076 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025150
 protein coding gene Chr2:606186-779947 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025785
 protein coding gene Chr2:587029-759358 (+)
PWK/PhJ MGP_PWKPhJ_G0024258
 protein coding gene Chr2:547414-718714 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024059
 protein coding gene Chr2:586550-768267 (+)
WSB/EiJ MGP_WSBEiJ_G0024578
 protein coding gene Chr2:591388-780537 (+)



Homology
more
  • Human Ortholog
    FAM107B, family with sequence similarity 107 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM107B, family with sequence similarity 107 member B
  • Synonyms
    C10orf45, HITS
  • Links
    NCBI Gene ID: 83641
    UniProt: Q9H098

  • Chr Location
    10p13; chr10:14518557-14774897 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit impaired hearing.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    21
  • cDNA Data
    159
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026655 Ensembl Gene Model | MGI Sequence Detail 211655 C57BL/6J ±  kb
    transcript ENSMUST00000226435 Ensembl | MGI Sequence Detail 3602 Not Applicable  
    polypeptide ENSMUSP00000154419 Ensembl | MGI Sequence Detail 307 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 159
      cDNA 159

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2138800, MGI:2138810, MGI:2138843, MGI:6468395
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 5
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/30/2025
    MGI 6.24     		The Jackson Laboratory