About   Help   FAQ
Rnf181 Gene Detail
Summary
  • Symbol
    Rnf181
  • Name
    ring finger protein 181
  • Synonyms
    1700047F16Rik, 2500002L14Rik, 6230415N01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913760
    NCBI Gene: 66510
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:72336697-72343939 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 32.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913760
 protein coding gene Chr6:72336695-72343977 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030873
 protein coding gene Chr6:72908567-72915809 (-)
A/J MGP_AJ_G0030843
 protein coding gene Chr6:70081795-70089027 (-)
AKR/J MGP_AKRJ_G0030772
 protein coding gene Chr6:72144219-72151427 (-)
BALB/cJ MGP_BALBcJ_G0030854
 protein coding gene Chr6:70110886-70118121 (-)
C3H/HeJ MGP_C3HHeJ_G0030858
 protein coding gene Chr6:112089641-112096862 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031312
 protein coding gene Chr6:74821009-74828239 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028501
 protein coding gene Chr6:69226975-69234426 (-)
CAST/EiJ MGP_CASTEiJ_G0029962
 protein coding gene Chr6:72007785-72015477 (-)
CBA/J MGP_CBAJ_G0030541
 protein coding gene Chr6:77871413-77878642 (-)
DBA/2J MGP_DBA2J_G0030693
 protein coding gene Chr6:69477395-69484627 (-)
FVB/NJ MGP_FVBNJ_G0030646
 protein coding gene Chr6:68859027-68866262 (-)
LP/J MGP_LPJ_G0030772
 protein coding gene Chr6:72815979-72823219 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030681
 protein coding gene Chr6:81261734-81268950 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031338
 protein coding gene Chr6:71956673-71963908 (-)
PWK/PhJ MGP_PWKPhJ_G0029678
 protein coding gene Chr6:68383102-68390504 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029506
 protein coding gene Chr6:70685870-70693177 (-)
WSB/EiJ MGP_WSBEiJ_G0030044
 protein coding gene Chr6:72320731-72327944 (-)



Homology
more
  • Human Ortholog
    RNF181, ring finger protein 181
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF181, ring finger protein 181
  • Synonyms
    HSPC238
  • Links
    NCBI Gene ID: 51255
    UniProt: Q9P0P0

  • Chr Location
    2p11.2; chr2:85595725-85597708 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    7
  • Endonuclease-mediated
    2
  • Gene trapped
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Rnf181
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    808
  • Tissues
    9
  • cDNA Data
    19
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055850 Ensembl Gene Model | MGI Sequence Detail 7243 C57BL/6J ±  kb
transcript ENSMUST00000114095 Ensembl | MGI Sequence Detail 869 Not Applicable  
polypeptide ENSMUSP00000109729 Ensembl | MGI Sequence Detail 206 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 4
Other
Accession IDs
less
MGI:1353556, MGI:1923395, MGI:1925597
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory