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Slc30a7
Gene Detail
Symbol

Name
ID
Slc30a7
solute carrier family 30 (zinc transporter), member 7
MGI:1913750
Synonyms
1810059J10Rik, 2610034N15Rik, 4833428C12Rik, ZnT7, ZnT-7
Feature Type
protein coding gene
Genetic Map
Chromosome 3
50.16 cM, cytoband G2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr3:115938973-116007406 bp, - strand
From NCBI annotation of GRCm38

  68434 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11332  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: cation efflux protein
Gene Tree: Slc30a7

Human
homologs
Human Homolog SLC30A7, solute carrier family 30 (zinc transporter), member 7
NCBI Gene ID 148867
neXtProt AC  NX_Q8NEW0
Human Synonyms  ZnT-7, ZNT7, ZnTL2
Human Chr (Location)  1p21.2; chr1:100896076-100997380 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(3) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trapped allele exhibit a low body zinc status, reduced food intake and poor body weight gain, and are lean due to a significant reduction in body fat accumulation; however, no signs of hair growth abnormalities or dermatitis are observed.
 
Interactions
Slc30a7 interacts with 492 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cation transport, ion transport, ...
Component cytoplasm, cytoplasmic membrane-bounded vesicle, ...
Function cation transmembrane transporter activity, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (49)    Tissues (49)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 49
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000054414 (Evidence)
Entrez Gene66500 (Evidence)
NIA Mouse Gene IndexU024563, U216804
Consensus CDS ProjectCCDS17783.1
International Mouse Knockout Project StatusSlc30a7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 66500 NCBI Gene Model | MGI Sequence Detail 68434 C57BL/6J ±  kb
transcript NM_023214 RefSeq | MGI Sequence Detail 9020 C57BL/6 
polypeptide Q9JKN1 UniProt | EBI | MGI Sequence Detail 378 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(671 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002524 Cation efflux protein
InterPro IPR027469 Cation efflux protein transmembrane domain
Protein Ontology PR:000015080 zinc transporter 7
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:190396 Huang L, et al., Znt7-null mice are more susceptible to diet-induced glucose intolerance and insulin resistance. J Biol Chem. 2012 Sep 28;287(40):33883-96
All references(36)
Other
accession IDs
MGI:1917163, MGI:2139735, MGI:3026979

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory