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Ndufb3 Gene Detail
Summary
  • Symbol
    Ndufb3
  • Name
    NADH:ubiquinone oxidoreductase subunit B3
  • Synonyms
    2700033I16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913745
    NCBI Gene: 66495
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:58586397-58595964 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 29.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913745
protein coding gene Chr1:58586384-58595964 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016055
protein coding gene Chr1:58472713-58481951 (+)
A/J MGP_AJ_G0016038
protein coding gene Chr1:56418782-56428152 (+)
AKR/J MGP_AKRJ_G0015994
protein coding gene Chr1:57941872-57952282 (+)
BALB/cJ MGP_BALBcJ_G0015993
protein coding gene Chr1:56448473-56459183 (+)
C3H/HeJ MGP_C3HHeJ_G0015825
protein coding gene Chr1:58207360-58217698 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016446
protein coding gene Chr1:60804087-60814615 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014168
protein coding gene Chr1:52349916-52359154 (+)
CAST/EiJ MGP_CASTEiJ_G0015407
protein coding gene Chr1:57455111-57464380 (+)
CBA/J MGP_CBAJ_G0015797
protein coding gene Chr1:62598635-62607886 (+)
DBA/2J MGP_DBA2J_G0015898
protein coding gene Chr1:55811252-55820391 (+)
FVB/NJ MGP_FVBNJ_G0015900
protein coding gene Chr1:55152590-55162380 (+)
LP/J MGP_LPJ_G0015970
protein coding gene Chr1:59358144-59367361 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015920
protein coding gene Chr1:65598091-65608899 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016493
protein coding gene Chr1:57913335-57922585 (+)
PWK/PhJ MGP_PWKPhJ_G0015194
protein coding gene Chr1:55212672-55222524 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014974
protein coding gene Chr1:57505712-57514953 (+)
WSB/EiJ MGP_WSBEiJ_G0015470
protein coding gene Chr1:57604475-57615456 (+)



Homology
more
  • Human Ortholog
    NDUFB3, NADH:ubiquinone oxidoreductase subunit B3
  • Vertebrate Orthologs
    12
  • Human Ortholog
    NDUFB3, NADH:ubiquinone oxidoreductase subunit B3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B12, CI-B12
  • Links
    NCBI Gene ID: 4709
    neXtProt AC: NX_O43676
    UniProt: O43676

  • Chr Location
    2q33.1; chr2:201071739-201085750 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 37630
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;3 macaque, rhesus
  • HCOP
    human homology predictions: NDUFB3
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human NDUFB3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Ndufb3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66495 NCBI Gene Model | MGI Sequence Detail 9568 C57BL/6J ±  kb
transcript NM_025597 RefSeq | MGI Sequence Detail 769 C57BL/6  
polypeptide Q9CQZ6 UniProt | EBI | MGI Sequence Detail 104 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000011087 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
  • PDB
  • InterPro Domains
    IPR012576 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Molecular
Reagents
less
  • All nucleic 92
    cDNA 92

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144808
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory