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Polr2l
Gene Detail
 Symbol
Name
ID
Polr2l
polymerase (RNA) II (DNA directed) polypeptide L
MGI:1913741
Synonyms 2510029B14Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
86.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:141471860-141475132 bp, - strand
From VEGA annotation of GRCm38

  3273 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129854  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: DNA-directed RNA polymerase II, RPB10/RpoN subunit type
Gene Tree: Polr2l

Human
homologs
Human Homolog POLR2L, polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
NCBI Gene ID 5441
neXtProt AC  NX_P62875
Human Synonyms  hRPB7.6, RBP10, RPABC5, RPB10, RPB10beta, RPB7.6
Human Chr (Location)  11p15; chr11:839721-842529 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(8) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Polr2l interacts with 129 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process transcription, DNA-templated, transcription from RNA polymerase II promoter
Component DNA-directed RNA polymerase I complex, DNA-directed RNA polymerase II, core complex, ...
Function DNA binding, DNA-directed RNA polymerase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (233)    Tissues (112)    Images (38)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 233
cDNA source data(72)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(73) cDNA(72) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000028947 (Evidence)
Ensembl Gene ModelENSMUSG00000038489 (Evidence)
Entrez Gene66491 (Evidence)
UniGene380115
DFCITC1576376, TC1617601
DoTSDT.94187049, DT.94187054
Consensus CDS ProjectCCDS52446.1
International Mouse Knockout Project StatusPolr2l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028947 VEGA Gene Model | MGI Sequence Detail 3273 C57BL/6J ±  kb
transcript OTTMUST00000071729 VEGA | MGI Sequence Detail 1650 Not Applicable 
polypeptide OTTMUSP00000036824 VEGA | MGI Sequence Detail 67 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10
InterPro IPR009057 Homeodomain-like
InterPro IPR020789 RNA polymerases, subunit N, zinc binding site
InterPro IPR023580 RNA polymerase subunit RPB10
Protein Ontology PR:000012999 DNA-directed RNA polymerases I, II, and III subunit RPABC5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory