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Polr2l
Gene Detail
Symbol

Name
ID
Polr2l
polymerase (RNA) II (DNA directed) polypeptide L
MGI:1913741
Synonyms
2510029B14Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 7
86.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:141471860-141475132 bp, - strand
From VEGA annotation of GRCm38

  3273 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:129854  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: POLR2L
Protein SuperFamily: DNA-directed RNA polymerase II, RPB10/RpoN subunit type
Gene Tree: Polr2l

Human
homologs
POLR2L, polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 5441
neXtProt AC: NX_P62875

Human Synonyms: hRPB7.6, RBP10, RPABC5, RPB10, RPB10beta, RPB7.6

Human Chr (Location): 11p15; chr11:839721-842529 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(8) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Polr2l interacts with 129 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (233)    Tissues (112)    Images (38)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 233
cDNA source data(72)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase polr2l.1, polr2l.2 ; ZFIN polr2l    NEW 
Molecular
reagents
All nucleic(73) cDNA(72) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000028947 (Evidence)
Ensembl Gene Model ENSMUSG00000038489 (Evidence)
Entrez Gene 66491 (Evidence)
UniGene 380115
DFCI TC1576376, TC1617601
DoTS DT.94187049, DT.94187054
Consensus CDS Project CCDS52446.1
International Mouse Phenotyping Consortium Status Polr2l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028947 VEGA Gene Model | MGI Sequence Detail 3273 C57BL/6J ±  kb
transcript OTTMUST00000071729 VEGA | MGI Sequence Detail 1650 Not Applicable 
polypeptide OTTMUSP00000036824 VEGA | MGI Sequence Detail 67 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10
InterPro IPR009057 Homeodomain-like
InterPro IPR020789 RNA polymerases, subunit N, zinc binding site
InterPro IPR023580 RNA polymerase subunit RPB10
Protein Ontology PR:000012999 DNA-directed RNA polymerases I, II, and III subunit RPABC5
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory