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Ska1 Gene Detail
Summary
  • Symbol
    Ska1
  • Name
    spindle and kinetochore associated complex subunit 1
  • Synonyms
    2810433K01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913718
    NCBI Gene: 66468
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:74328370-74340889 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 50.67 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    161 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913718
protein coding gene Chr18:74328370-74340889 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024554
protein coding gene Chr18:74817099-74829633 (-)
A/J MGP_AJ_G0024521
protein coding gene Chr18:71556720-71569275 (-)
AKR/J MGP_AKRJ_G0024492
protein coding gene Chr18:73678450-73692760 (-)
BALB/cJ MGP_BALBcJ_G0024521
protein coding gene Chr18:71729299-71741854 (-)
C3H/HeJ MGP_C3HHeJ_G0024289
protein coding gene Chr18:73764127-73776504 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024967
protein coding gene Chr18:76776677-76791029 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022398
protein coding gene Chr18:70654090-70665853 (-)
CAST/EiJ MGP_CASTEiJ_G0023762
protein coding gene Chr18:73939732-73958071 (-)
CBA/J MGP_CBAJ_G0024258
protein coding gene Chr18:79390819-79403392 (-)
DBA/2J MGP_DBA2J_G0024388
protein coding gene Chr18:71149154-71161748 (-)
FVB/NJ MGP_FVBNJ_G0024354
protein coding gene Chr18:70492657-70507144 (-)
LP/J MGP_LPJ_G0024472
protein coding gene Chr18:74689549-74702024 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024384
protein coding gene Chr18:80853381-80867605 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025015
protein coding gene Chr18:73805927-73818793 (-)
PWK/PhJ MGP_PWKPhJ_G0023506
protein coding gene Chr18:71513779-71527045 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023311
protein coding gene Chr18:73967864-73980600 (-)
WSB/EiJ MGP_WSBEiJ_G0023825
protein coding gene Chr18:73758905-73771768 (-)



Homology
more
  • Human Ortholog
    SKA1, spindle and kinetochore associated complex subunit 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SKA1, spindle and kinetochore associated complex subunit 1
  • Synonyms
    C18orf24
  • Links
    NCBI Gene ID: 220134
    neXtProt AC: NX_Q96BD8
    UniProt: Q96BD8

  • Chr Location
    18q21.1; chr18:50375040-50394168 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66468 NCBI Gene Model | MGI Sequence Detail 12520 C57BL/6J ±  kb
transcript NM_025581 RefSeq | MGI Sequence Detail 2669 C57BL/6  
polypeptide Q9CPV1 UniProt | EBI | MGI Sequence Detail 254 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147335
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:314103 Ulmke PA, et al., Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory