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Taf12 Gene Detail
Summary
  • Symbol
    Taf12
  • Name
    TATA-box binding protein associated factor 12
  • Synonyms
    20kDa, 2810422D08Rik, Taf2J
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913714
    NCBI Gene: 66464
  • Gene Overview
    MyGene.info: TAF12
Location & Maps
more
  • Sequence Map
    Chr4:132274375-132295766 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21392 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    TAF12, TATA-box binding protein associated factor 12
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TAF12, TATA-box binding protein associated factor 12
    Orthology source: HomoloGene
  • Synonyms
    TAF2J, TAFII20
  • Links
    NCBI Gene ID: 6883
    neXtProt AC: NX_Q16514

  • Chr Location
    1p35.3; chr1:28603096-28643109 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 68477
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: TAF12
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    65
  • Chemically induced (other)
    2
  • Gene trapped
    60
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Taf12
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011107 VEGA Gene Model | MGI Sequence Detail 21392 C57BL/6J ±  kb
transcript OTTMUST00000026005 VEGA | MGI Sequence Detail 777 Not Applicable  
polypeptide OTTMUSP00000011908 VEGA | MGI Sequence Detail 213 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    181 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016017 transcription initiation factor TFIID subunit 12
  • InterPro Domains
    IPR009072 Histone-fold
    IPR003228 Transcription initiation factor TFIID
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140602
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory