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Taf12 Gene Detail
Summary
  • Symbol
    Taf12
  • Name
    TATA-box binding protein associated factor 12
  • Synonyms
    20kDa, 2810422D08Rik, Taf2J
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913714
    NCBI Gene: 66464
  • Gene Overview
    MyGene.info: TAF12
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:132274355-132293329 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 65.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913714
protein coding gene Chr4:132274355-132295766 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028866
protein coding gene Chr4:134410382-134435102 (+)
A/J MGP_AJ_G0028825
protein coding gene Chr4:128828512-128850019 (+)
AKR/J MGP_AKRJ_G0028778
protein coding gene Chr4:132448484-132470755 (+)
BALB/cJ MGP_BALBcJ_G0028848
protein coding gene Chr4:129440054-129461467 (+)
C3H/HeJ MGP_C3HHeJ_G0028562
protein coding gene Chr4:132701755-132725087 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029290
protein coding gene Chr4:139260944-139283661 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026562
protein coding gene Chr4:121907938-121910466 (+)
CAST/EiJ MGP_CASTEiJ_G0027995
protein coding gene Chr4:130770447-130797174 (+)
CBA/J MGP_CBAJ_G0028528
protein coding gene Chr4:142828401-142857187 (+)
DBA/2J MGP_DBA2J_G0028677
protein coding gene Chr4:129252193-129274147 (+)
FVB/NJ MGP_FVBNJ_G0028644
protein coding gene Chr4:128100601-128122574 (+)
LP/J MGP_LPJ_G0028778
protein coding gene Chr4:134568504-134592444 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028670
protein coding gene Chr4:147425429-147449896 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029328
protein coding gene Chr4:132850170-132871198 (+)
PWK/PhJ MGP_PWKPhJ_G0027716
protein coding gene Chr4:125931110-125950667 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027542
protein coding gene Chr4:128720976-128746481 (+)
WSB/EiJ MGP_WSBEiJ_G0028075
protein coding gene Chr4:133032577-133055510 (+)



Homology
more
  • Human Ortholog
    TAF12, TATA-box binding protein associated factor 12
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TAF12, TATA-box binding protein associated factor 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TAF2J, TAFII20
  • Links
    NCBI Gene ID: 6883
    neXtProt AC: NX_Q16514
    UniProt: Q16514

  • Chr Location
    1p35.3; chr1:28603096-28648707 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 68477
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TAF12
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    65
  • Chemically induced (other)
    2
  • Gene trapped
    60
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Taf12
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66464 NCBI Gene Model | MGI Sequence Detail 18975 C57BL/6J ±  kb
transcript NM_025579 RefSeq | MGI Sequence Detail 1353 C57BL/6  
polypeptide Q8VE65 UniProt | EBI | MGI Sequence Detail 161 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR009072 Histone-fold
    IPR037794 Transcription initiation factor TFIID subunit 12
    IPR003228 Transcription initiation factor TFIID subunit 12 domain
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140602
References
more
  • Summaries
    All 43
    Developmental Gene Expression 9
    Gene Ontology 9
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:245730 Bardot P, et al., The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. Development. 2017 Oct 15;144(20):3808-3818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory