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Cyc1
Gene Detail
Symbol

Name
ID
Cyc1
cytochrome c-1
MGI:1913695
Synonyms
2610002H19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 15
35.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:76343523-76345934 bp, + strand
From NCBI annotation of GRCm38

  2412 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55617  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: cytochrome c1, heme protein
Gene Tree: Cyc1

Human
homologs
Human Homolog CYC1, cytochrome c-1
NCBI Gene ID 1537
neXtProt AC  NX_P08574
Human Synonyms  MC3DN6, UQCR4
Human Chr (Location)  8q24.3; chr8:144095035-144097527 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYC1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Radiation induced(1) Targeted(1)
Genomic Mutations involving Cyc1 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyc1 interacts with 18 markers (Mir27b, Mir31, Mir32, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process oxidation-reduction process, response to glucagon, ...
Component integral component of membrane, membrane, ...
Function electron carrier activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (100)    Tissues (96)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 98
RT-PCR 2
cDNA source data(250)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(251) cDNA(250) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000022551 (Evidence)
Entrez Gene66445 (Evidence)
UniGene29196
DFCITC1738341, TC1573549
DoTSDT.55254812, DT.101398966, DT.101315232
NIA Mouse Gene IndexU016364
Consensus CDS ProjectCCDS27567.1
International Mouse Knockout Project StatusCyc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 66445 NCBI Gene Model | MGI Sequence Detail 2412 C57BL/6J ±  kb
transcript NM_025567 RefSeq | MGI Sequence Detail 1194 C57BL/6 
polypeptide Q9D0M3 UniProt | EBI | MGI Sequence Detail 325 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(2 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002326 Cytochrome c1
InterPro IPR021157 Cytochrome c1, transmembrane anchor, C-terminal
InterPro IPR009056 Cytochrome c domain
Protein Ontology PR:000006089 cytochrome c1, heme protein, mitochondrial
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193725 Kuang E, et al., Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection. PLoS Genet. 2012;8(10):e1003007
All references(40)
Other
accession IDs
MGI:2145898

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory