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Cyc1 Gene Detail
Summary
  • Symbol
    Cyc1
  • Name
    cytochrome c-1
  • Synonyms
    2610002H19Rik, Cyct1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913695
    NCBI Gene: 66445
  • Gene Overview
    MyGene.info: CYC1
Location & Maps
more
  • Sequence Map
    Chr15:76343523-76345934 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2412 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 35.74 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CYC1, cytochrome c1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CYC1, cytochrome c1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MC3DN6, UQCR4
  • Links
    NCBI Gene ID: 1537
    neXtProt AC: NX_P08574

  • Chr Location
    8q24.3; chr8:144095035-144097527 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CYC1 associations

Human Disease Mouse Models
       Mitochondrial Complex III Deficiency, Nuclear Type 6; MC3DN6   OMIM: 615453
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    3
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Cyc1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66445 NCBI Gene Model | MGI Sequence Detail 2412 C57BL/6J ±  kb
transcript NM_025567 RefSeq | MGI Sequence Detail 1194 C57BL/6  
polypeptide Q9D0M3 UniProt | EBI | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000006089 cytochrome c1, heme protein, mitochondrial
  • InterPro Domains
    IPR002326 Cytochrome c1
    IPR021157 Cytochrome c1, transmembrane anchor, C-terminal
    IPR009056 Cytochrome c-like domain
Molecular
Reagents
less
  • All nucleic 251
    cDNA 250
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145898
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 9
    Phenotypes 27
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:224980 Lee KY, et al., Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism. Nat Commun. 2015;6:8054

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory