About   Help   FAQ
Tnfaip8l1 Gene Detail
Summary
  • Symbol
    Tnfaip8l1
  • Name
    tumor necrosis factor, alpha-induced protein 8-like 1
  • Synonyms
    2600017J23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913693
    NCBI Gene: 66443
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:56162491-56173955 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 29.19 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913693
protein coding gene Chr17:56162477-56173955 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023916
protein coding gene Chr17:57815869-57828499 (+)
A/J MGP_AJ_G0023875
protein coding gene Chr17:56252452-56263924 (+)
AKR/J MGP_AKRJ_G0023845
protein coding gene Chr17:56925625-56937004 (+)
BALB/cJ MGP_BALBcJ_G0023877
protein coding gene Chr17:56076382-56088023 (+)
C3H/HeJ MGP_C3HHeJ_G0023640
protein coding gene Chr17:57637499-57648956 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024321
protein coding gene Chr17:60094568-60105972 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021768
protein coding gene Chr17:52750056-52761404 (+)
CAST/EiJ MGP_CASTEiJ_G0023123
protein coding gene Chr17:57948153-57959588 (+)
CBA/J MGP_CBAJ_G0023617
protein coding gene Chr17:62395005-62406752 (+)
DBA/2J MGP_DBA2J_G0023745
protein coding gene Chr17:54967992-54979847 (+)
FVB/NJ MGP_FVBNJ_G0023711
protein coding gene Chr17:54491179-54502636 (+)
LP/J MGP_LPJ_G0023825
protein coding gene Chr17:58516151-58527872 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023738
protein coding gene Chr17:61944743-61956139 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024366
protein coding gene Chr17:57301379-57315889 (+)
PWK/PhJ MGP_PWKPhJ_G0022868
protein coding gene Chr17:54315471-54327977 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022680
protein coding gene Chr17:54067699-54083377 (+)
WSB/EiJ MGP_WSBEiJ_G0023187
protein coding gene Chr17:57914017-57926711 (+)



Homology
more
  • Human Ortholog
    TNFAIP8L1, TNF alpha induced protein 8 like 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TNFAIP8L1, TNF alpha induced protein 8 like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TIPE1
  • Links
    NCBI Gene ID: 126282
    neXtProt AC: NX_Q8WVP5
    UniProt: Q8WVP5

  • Chr Location
    19p13.3; chr19:4639505-4655568 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66443 NCBI Gene Model | MGI Sequence Detail 11465 C57BL/6J ±  kb
transcript NM_025566 RefSeq | MGI Sequence Detail 2365 C57BL/6  
polypeptide Q8K288 UniProt | EBI | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000016477 tumor necrosis factor alpha-induced protein 8-like protein 1
  • InterPro Domains
    IPR038355 TNFAIP8 superfamily
    IPR008477 Tumor necrosis factor alpha-induced protein 8-like
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory