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Magohb Gene Detail
Summary
  • Symbol
    Magohb
  • Name
    mago homolog B, exon junction complex core component
  • Synonyms
    2010012C16Rik, Magoh-rs1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913691
    NCBI Gene: 66441
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:131284389-131293244 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 63.44 cM, cytoband C7
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913691
protein coding gene Chr6:131284388-131293244 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031366
protein coding gene Chr6:135215014-135223406 (-)
A/J MGP_AJ_G0031343
protein coding gene Chr6:129961739-129970897 (-)
AKR/J MGP_AKRJ_G0031271
protein coding gene Chr6:133749280-133758171 (-)
BALB/cJ MGP_BALBcJ_G0031350
protein coding gene Chr6:129634434-129643238 (-)
C3H/HeJ MGP_C3HHeJ_G0031073
protein coding gene Chr6:133835341-133845012 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031808
protein coding gene Chr6:138832043-138841817 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028945
protein coding gene Chr6:128254613-128263424 (-)
CAST/EiJ MGP_CASTEiJ_G0030444
protein coding gene Chr6:133748604-133757360 (-)
CBA/J MGP_CBAJ_G0031031
protein coding gene Chr6:144160200-144169028 (-)
DBA/2J MGP_DBA2J_G0031191
protein coding gene Chr6:128870813-128879709 (-)
FVB/NJ MGP_FVBNJ_G0031140
protein coding gene Chr6:127772993-127781584 (-)
LP/J MGP_LPJ_G0031271
protein coding gene Chr6:135526935-135535721 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031177
protein coding gene Chr6:147947844-147958348 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031841
protein coding gene Chr6:133620015-133628677 (-)
PWK/PhJ MGP_PWKPhJ_G0030164
protein coding gene Chr6:127263975-127273127 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029992
protein coding gene Chr6:131871972-131882371 (-)
WSB/EiJ MGP_WSBEiJ_G0030531
protein coding gene Chr6:134192249-134201709 (-)



Homology
more
  • Human Ortholog
    MAGOHB, mago homolog B, exon junction complex subunit
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MAGOHB, mago homolog B, exon junction complex subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    mago, magoh, MGN2
  • Links
    NCBI Gene ID: 55110
    neXtProt AC: NX_Q96A72
    UniProt: Q96A72

  • Chr Location
    12p13.2; chr12:10604190-10613609 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66441 NCBI Gene Model | MGI Sequence Detail 8856 C57BL/6J ±  kb
transcript NM_001327860 RefSeq | MGI Sequence Detail 966 C57BL/6  
polypeptide Q9CQL1 UniProt | EBI | MGI Sequence Detail 146 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR004023 Mago nashi protein
    IPR036605 Mago nashi superfamily
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 3
Other
Accession IDs
less
MGI:1889515
References
more
  • Summaries
    All 26
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:62862 Depatie C, et al., Sequence-ready BAC contig, physical, and transcriptional map of a 2-Mb region overlapping the mouse chromosome 6 host-resistance locus Cmv1. Genomics. 2000 Jun 1;66(2):161-74
  • Latest
    J:203327 Ladopoulos V, et al., The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter. Mol Cell Biol. 2013 Apr;33(7):1383-93

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory