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Rtf2 Gene Detail
Summary
  • Symbol
    Rtf2
  • Name
    replication termination factor 2
  • Synonyms
    1700067C04Rik, 2410001C21Rik, 5730427M17Rik, Rtfdc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913654
    NCBI Gene: 66404
  • Gene Overview
    MyGene.info: RTF2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:172440578-172469899 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 94.86 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    302 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913654
protein coding gene Chr2:172440556-172469908 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026945
protein coding gene Chr2:178612910-178642654 (+)
A/J MGP_AJ_G0026912
protein coding gene Chr2:171135506-171165492 (+)
AKR/J MGP_AKRJ_G0026883
protein coding gene Chr2:176303832-176335161 (+)
BALB/cJ MGP_BALBcJ_G0026921
protein coding gene Chr2:171526608-171563314 (+)
C3H/HeJ MGP_C3HHeJ_G0026663
protein coding gene Chr2:176654673-176685598 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027368
protein coding gene Chr2:183780216-183811201 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024738
protein coding gene Chr2:164383741-164414645 (+)
CAST/EiJ MGP_CASTEiJ_G0026121
protein coding gene Chr2:177325350-177356247 (+)
CBA/J MGP_CBAJ_G0026640
protein coding gene Chr2:190638901-190668222 (+)
DBA/2J MGP_DBA2J_G0026778
protein coding gene Chr2:170230188-170259514 (+)
FVB/NJ MGP_FVBNJ_G0026744
protein coding gene Chr2:168831890-168861842 (+)
LP/J MGP_LPJ_G0026879
protein coding gene Chr2:178544859-178575528 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026763
protein coding gene Chr2:193627849-193662202 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027425
protein coding gene Chr2:176272009-176302296 (+)
PWK/PhJ MGP_PWKPhJ_G0025858
protein coding gene Chr2:169989597-170027331 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025658
protein coding gene Chr2:175270178-175300887 (+)
WSB/EiJ MGP_WSBEiJ_G0026194
protein coding gene Chr2:177245407-177274759 (+)



Homology
more
  • Human Ortholog
    RTF2, replication termination factor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RTF2, replication termination factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf43, CDAO5, HSPC164, RTFDC1, SHUJUN-3
  • Links
    NCBI Gene ID: 51507
    neXtProt AC: NX_Q9BY42
    UniProt: Q9BY42

  • Chr Location
    20q13.31; chr20:56468585-56518886 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9501
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RTF2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66404 NCBI Gene Model | MGI Sequence Detail 29322 C57BL/6J ±  kb
transcript NM_025542 RefSeq | MGI Sequence Detail 2142 C57BL/6  
polypeptide Q99K95 UniProt | EBI | MGI Sequence Detail 307 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR006735 Replication termination factor 2
    IPR027799 Replication termination factor 2, RING-finger
Molecular
Reagents
less
  • All nucleic 160
    cDNA 160

    Microarray probesets 3
Other
Accession IDs
less
MGI:1921524, MGI:2138797
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory