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Sln
Gene Detail
Symbol

Name
ID
Sln
sarcolipin
MGI:1913652
Synonyms
2310045A07Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
29.24 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:53850251-53853844 bp, + strand
From Ensembl annotation of GRCm38

  3594 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: sarcolipin
Gene Tree: Sln
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(3) Targeted(6)
Incidental mutations (data from APF )
 
Mice homozygous for a null allele exhibit increased cardiac contractility.
 
Interactions
Sln interacts with 41 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process regulation of calcium-transporting ATPase activity, regulation of relaxation of muscle, ...
Component cell, endoplasmic reticulum, ...
Function enzyme regulator activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (63)    Tissues (7)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 63
cDNA source data(50)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(50) cDNA(50)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000042045 (Evidence)
Entrez Gene66402 (Evidence)
UniGene29132
DFCITC1578933
DoTSDT.535982
NIA Mouse Gene IndexU010503
Consensus CDS ProjectCCDS40640.1
International Mouse Knockout Project StatusSln
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042045 Ensembl Gene Model | MGI Sequence Detail 3594 C57BL/6J ±  kb
transcript ENSMUST00000048485 Ensembl | MGI Sequence Detail 515 Not Applicable 
polypeptide ENSMUSP00000036950 Ensembl | MGI Sequence Detail 31 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008028 Sarcolipin
Protein Ontology PR:000015247 sarcolipin
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201178 Bombardier E, et al., Sarcolipin trumps beta-adrenergic receptor signaling as the favored mechanism for muscle-based diet-induced thermogenesis. FASEB J. 2013 Sep;27(9):3871-8
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory