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Sar1b Gene Detail
Summary
  • Symbol
    Sar1b
  • Name
    secretion associated Ras related GTPase 1B
  • Synonyms
    2310075M17Rik, 2900019I22Rik, Sara2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913647
    NCBI Gene: 66397
  • Gene Overview
    MyGene.info: SAR1B
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:51763687-51791925 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 31.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913647
protein coding gene Chr11:51763663-51791953 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018276
protein coding gene Chr11:51032075-51061541 (+)
A/J MGP_AJ_G0018245
protein coding gene Chr11:49102033-49130057 (+)
AKR/J MGP_AKRJ_G0018215
protein coding gene Chr11:50644556-50675528 (+)
BALB/cJ MGP_BALBcJ_G0018216
protein coding gene Chr11:49401384-49430315 (+)
C3H/HeJ MGP_C3HHeJ_G0018027
protein coding gene Chr11:50676788-50705204 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018666
protein coding gene Chr11:52569689-52598679 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016318
protein coding gene Chr11:46659274-46686017 (+)
CAST/EiJ MGP_CASTEiJ_G0017591
protein coding gene Chr11:50672305-50702595 (+)
CBA/J MGP_CBAJ_G0018002
protein coding gene Chr11:55039449-55067632 (+)
DBA/2J MGP_DBA2J_G0018109
protein coding gene Chr11:48805166-48834151 (+)
FVB/NJ MGP_FVBNJ_G0018104
protein coding gene Chr11:48523535-48554871 (+)
LP/J MGP_LPJ_G0018185
protein coding gene Chr11:51444380-51472843 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018127
protein coding gene Chr11:56443242-56478813 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018709
protein coding gene Chr11:50747526-50775009 (+)
PWK/PhJ MGP_PWKPhJ_G0017367
protein coding gene Chr11:49329650-49357516 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017162
protein coding gene Chr11:50479111-50510003 (+)
WSB/EiJ MGP_WSBEiJ_G0017639
protein coding gene Chr11:50388241-50417391 (+)



Homology
more
  • Human Ortholog
    SAR1B, secretion associated Ras related GTPase 1B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SAR1B, secretion associated Ras related GTPase 1B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ANDD, CMRD, GTBPB, SARA2
  • Links
    NCBI Gene ID: 51128
    neXtProt AC: NX_Q9Y6B6
    UniProt: Q9Y6B6

  • Chr Location
    5q31.1; chr5:134601149-134632843 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human SAR1B associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020386 Ensembl Gene Model | MGI Sequence Detail 28239 C57BL/6J ±  kb
transcript ENSMUST00000020653 Ensembl | MGI Sequence Detail 1201 Not Applicable  
polypeptide ENSMUSP00000020653 Ensembl | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 131
    cDNA 131

    Microarray probesets 4
Other
Accession IDs
less
MGI:1920195
References
more
  • Summaries
    All 40
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:221071 Chang HM, et al., The FYVE domain of Smad Anchor for Receptor Activation (SARA) is required to prevent skin carcinogenesis, but not in mouse development. PLoS One. 2014;9(8):e105299

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory