Cutc Gene Detail

Summary

• Symbol
  Cutc
• Name
  cutC copper transporter
• Synonyms
  2310039I18Rik, CGI-32

• Feature Type
  protein coding gene
• IDs
  MGI:1913638
  NCBI Gene: 66388
• Gene Overview
  MyGene.info: CUTC
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr19:43753023-43768638 bp, + strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, 36.67 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  165 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913638	protein coding gene	Chr19:43752996-43768638 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025157	protein coding gene	Chr19:43173552-43193078 (+)
A/J	MGP_AJ_G0025134	protein coding gene	Chr19:41117277-41133284 (+)
AKR/J	MGP_AKRJ_G0025102	protein coding gene	Chr19:42414924-42430539 (+)
BALB/cJ	MGP_BALBcJ_G0025128	protein coding gene	Chr19:41164452-41180255 (+)
C3H/HeJ	MGP_C3HHeJ_G0024888	protein coding gene	Chr19:42597934-42614228 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025571	protein coding gene	Chr19:44242185-44260584 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022985	protein coding gene	Chr19:40410278-40426184 (+)
CAST/EiJ	MGP_CASTEiJ_G0024353	protein coding gene	Chr19:42285169-42302615 (+)
CBA/J	MGP_CBAJ_G0024868	protein coding gene	Chr19:46437384-46454716 (+)
DBA/2J	MGP_DBA2J_G0025000	protein coding gene	Chr19:40944048-40959759 (+)
FVB/NJ	MGP_FVBNJ_G0024961	protein coding gene	Chr19:40698803-40714450 (+)
LP/J	MGP_LPJ_G0025086	protein coding gene	Chr19:43139636-43155774 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024992	protein coding gene	Chr19:45978909-45994652 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025629	protein coding gene	Chr19:42511119-42527262 (+)
PWK/PhJ	MGP_PWKPhJ_G0024102	protein coding gene	Chr19:40841989-40858691 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023906	protein coding gene	Chr19:41227129-41245647 (+)
WSB/EiJ	MGP_WSBEiJ_G0024423	protein coding gene	Chr19:42649628-42665268 (+)

Homology

• Human Ortholog
  CUTC, cutC copper transporter

• Vertebrate Orthologs
  10

• Human Ortholog
  CUTC, cutC copper transporter
  Orthology source: HomoloGene, HGNC
• Synonyms
  CGI-32
• Links
  HGNC:24271

  NCBI Gene ID: 51076

  neXtProt AC: NX_Q9NTM9

  UniProt: Q9NTM9

  
  
• Chr Location
  10q24.2; chr10:99732201-99756137 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 9318
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: CUTC
• Gene Tree
  Cutc
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  6
• Gene trapped
  3
• Targeted
  3
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  3 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  10
• GO References
  3

• External Resources
  FuncBase

Expression

• cDNA Data
  19

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase cutc
  ZFIN cutc

Interactions

• Cutc interacts with 42 markers (Mir1a-1, Mir1a-2, Mir10a, ...) View All

Sequences &
Gene Models

• All Sequences
  43
• RefSeq
  4
• UniProt
  4
• CCDS
  CCDS29837.1, CCDS50443.1
• UniGene
  20257

• Ensembl
  ENSMUSG00000025193 (Evidence)
• NCBI Gene
  66388

Representative Sequences			Length	Strain/Species
genomic	66388	NCBI Gene Model | MGI Sequence Detail	15616	C57BL/6J
transcript	NM_001113562	RefSeq | MGI Sequence Detail	1308	C57BL/6
polypeptide	Q9D8X1	UniProt | EBI | MGI Sequence Detail	272	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000006055 copper homeostasis protein cutC
  (term hierarchy)
• InterPro Domains
  IPR023648 Copper homeostasis CutC domain
  IPR036822 Copper homeostasis (CutC) domain superfamily
  IPR005627 Copper homeostasis protein CutC

Molecular
Reagents

• All nucleic 19

  cDNA 19

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2147511

References

• Summaries
  All 28

  Gene Ontology 3

  Phenotypes 6
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Cutc:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr156530	Chr19:43752992-43753064 (+)	5 bp
Tssr156531	Chr19:43753074-43753110 (+)	69 bp
Tssr156532	Chr19:43753112-43753131 (+)	99 bp