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Ppp1r7 Gene Detail
Summary
  • Symbol
    Ppp1r7
  • Name
    protein phosphatase 1, regulatory (inhibitor) subunit 7
  • Synonyms
    2310014J01Rik, SDS22
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913635
    NCBI Gene: 66385
  • Gene Overview
    MyGene.info: PPP1R7
Location & Maps
more
  • Sequence Map
    Chr1:93342854-93373489 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30636 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 47.24 cM, cytoband D
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PPP1R7, protein phosphatase 1 regulatory subunit 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPP1R7, protein phosphatase 1 regulatory subunit 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SDS22
  • Links
    NCBI Gene ID: 5510
    neXtProt AC: NX_Q15435

  • Chr Location
    2q37.3; chr2:241149573-241183650 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2032
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PPP1R7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Ppp1r7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021853 VEGA Gene Model | MGI Sequence Detail 30636 C57BL/6J ±  kb
transcript OTTMUST00000051857 VEGA | MGI Sequence Detail 10315 Not Applicable  
polypeptide OTTMUSP00000024475 VEGA | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    123 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013130 protein phosphatase 1 regulatory subunit 7
  • InterPro Domains
    IPR007632 Anoctamin
    IPR001611 Leucine-rich repeat
    IPR025875 Leucine rich repeat 4
    IPR032675 Leucine-rich repeat domain, L domain-like
    IPR003591 Leucine-rich repeat, typical subtype
    IPR003603 U2A'/phosphoprotein 32 family A, C-terminal
Molecular
Reagents
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  • All nucleic 132
    cDNA 132

    Microarray probesets 5
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:7552 Hashimoto Y, et al., Genetically regulated expression of UDP-N-acetylgalactosamine: GM3(NeuGc) N-acetylgalactosaminyltransferase [EC 2.4.1.92] activity in mouse liver. J Biochem. 1984 Jun;95(6):1543-9
  • Latest
    J:191006 Wurzenberger C, et al., Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J Cell Biol. 2012 Jul 23;198(2):173-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory