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Ostc Gene Detail
Summary
  • Symbol
    Ostc
  • Name
    oligosaccharyltransferase complex subunit (non-catalytic)
  • Synonyms
    2310008M10Rik, 5730557H03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913607
    NCBI Gene: 66357
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:130489566-130503093 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 60.53 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    496 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913607
 protein coding gene Chr3:130489561-130503093 (-)
129S1/SvImJ ENSMUSG00200002971
 protein coding gene Chr3:127261721-127275298 (-)
A/J ENSMUSG00195008272
 protein coding gene Chr3:127377261-127390794 (-)
AKR/J ENSMUSG00220022352
 protein coding gene Chr3:125817997-125831573 (-)
BALB/cJ ENSMUSG00180003656
 protein coding gene Chr3:127305908-127319723 (-)
C3H/HeJ ENSMUSG00175012946
 protein coding gene Chr3:126883079-126896668 (-)
C57BL/6NJ ENSMUSG00215013309
 protein coding gene Chr3:127639014-127652548 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025635
 protein coding gene Chr3:124284319-124297062 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210003362
 protein coding gene Chr3:127480829-127494362 (-)
DBA/2J ENSMUSG00185024708
 protein coding gene Chr3:128104751-128118340 (-)
FVB/NJ ENSMUSG00205016948
 protein coding gene Chr3:126431188-126444765 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230003775
 protein coding gene Chr3:130081986-130095564 (-)
NOD/ShiLtJ ENSMUSG00190001105
 protein coding gene Chr3:128495767-128509347 (-)
NZO/HlLtJ ENSMUSG00225005581
 protein coding gene Chr3:132534863-132548443 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OSTC, oligosaccharyltransferase complex non-catalytic subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OSTC, oligosaccharyltransferase complex non-catalytic subunit
  • Synonyms
    DC2
  • Links
    NCBI Gene ID: 58505
    UniProt: Q9NRP0

  • Chr Location
    4q25; chr4:108650585-108667820 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    8
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Ostc
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    653
  • Tissues
    15
  • cDNA Data
    127
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66357 NCBI Gene Model | MGI Sequence Detail 13528 C57BL/6J ±  kb
transcript NM_025509 RefSeq | MGI Sequence Detail 1081 C57BL/6  
polypeptide Q78XF5 UniProt | EBI | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 128
    cDNA 128

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917910
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:319945 Ramirez AS, et al., Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B. Science. 2019 Dec 13;366(6471):1372-1375
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory