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Gmpr Gene Detail
Summary
  • Symbol
    Gmpr
  • Name
    guanosine monophosphate reductase
  • Synonyms
    2310004P21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913605
    NCBI Gene: 66355
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:45507444-45546386 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 21.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    367 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913605
protein coding gene Chr13:45507444-45553800 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020508
protein coding gene Chr13:44221597-44268158 (+)
A/J MGP_AJ_G0020462
protein coding gene Chr13:42681912-42721349 (+)
AKR/J MGP_AKRJ_G0020439
protein coding gene Chr13:43869925-43908551 (+)
BALB/cJ MGP_BALBcJ_G0020458
protein coding gene Chr13:42890649-42929853 (+)
C3H/HeJ MGP_C3HHeJ_G0020257
protein coding gene Chr13:43707396-43747856 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020891
protein coding gene Chr13:45567674-45607325 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018478
protein coding gene Chr13:40755350-40794650 (+)
CAST/EiJ MGP_CASTEiJ_G0019772
protein coding gene Chr13:43645192-43684347 (+)
CBA/J MGP_CBAJ_G0020218
protein coding gene Chr13:47457953-47504715 (+)
DBA/2J MGP_DBA2J_G0020340
protein coding gene Chr13:42252592-42291423 (+)
FVB/NJ MGP_FVBNJ_G0020319
protein coding gene Chr13:41770978-41810387 (+)
LP/J MGP_LPJ_G0020415
protein coding gene Chr13:44443592-44482817 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020348
protein coding gene Chr13:47323186-47362392 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020934
protein coding gene Chr13:43542589-43582700 (+)
PWK/PhJ MGP_PWKPhJ_G0019528
protein coding gene Chr13:42367687-42407637 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019356
protein coding gene Chr13:42212692-42252862 (+)
WSB/EiJ MGP_WSBEiJ_G0019834
protein coding gene Chr13:43858069-43898140 (+)



Homology
more
  • Human Ortholog
    GMPR, guanosine monophosphate reductase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GMPR, guanosine monophosphate reductase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GMPR1, GMPR 1
  • Links
    NCBI Gene ID: 2766
    neXtProt AC: NX_P36959
    UniProt: P36959

  • Chr Location
    6p22.3; chr6:16238580-16295549 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66355 NCBI Gene Model | MGI Sequence Detail 38943 C57BL/6J ±  kb
transcript NM_025508 RefSeq | MGI Sequence Detail 1584 C57BL/6  
polypeptide Q9DCZ1 UniProt | EBI | MGI Sequence Detail 345 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 66
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145389
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:186666 Pang CJ, et al., Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis. Mol Cell Biol. 2012 Jul;32(13):2628-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory