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Pla2g12a
Gene Detail
Symbol

Name
ID
Pla2g12a
phospholipase A2, group XIIA
MGI:1913600
Synonyms
2310004B05Rik, GXII, MGC:58884, mGXII-1, Pla2g12, Rossy
Feature Type
protein coding gene
Genetic Map
Chromosome 3
59.40 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:129878606-129895825 bp, + strand
From VEGA annotation of GRCm38

  17220 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11328  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PLA2G12A
Gene Tree: Pla2g12a

Human
homologs
PLA2G12A, phospholipase A2, group XIIA
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 81579
neXtProt AC: NX_Q9BZM1

Human Synonyms: GXII, PLA2G12, ROSSY

Human Chr (Location): 4q25; chr4:109709989-109730086 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Pla2g12a interacts with 109 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process lipid catabolic process, lipid metabolic process, ...
Component cytoplasm, endoplasmic reticulum, ...
Function calcium ion binding, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (141)    Tissues (120)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 117
RT-PCR 24
cDNA source data(54)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase pla2g12a ; ZFIN pla2g12a    NEW 
Molecular
reagents
All nucleic(57) cDNA(54) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000054638 (Evidence)
Ensembl Gene Model ENSMUSG00000027999 (Evidence)
Entrez Gene 66350 (Evidence)
UniGene 151951
DFCI TC1580570, TC1593309, TC1593542
DoTS DT.101122564, DT.101122567, DT.101356174, DT.532926
NIA Mouse Gene Index U003846
EC 3.1.1.4
Consensus CDS Project CCDS17836.1, CCDS17837.1
International Mouse Phenotyping Consortium Status Pla2g12a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000054638 VEGA Gene Model | MGI Sequence Detail 17220 C57BL/6J ±  kb
transcript OTTMUST00000135459 VEGA | MGI Sequence Detail 1561 Not Applicable 
polypeptide OTTMUSP00000071674 VEGA | MGI Sequence Detail 192 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(7) UniProt(4)
Polymorphisms
SNPs within 2kb(285 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013090 Phospholipase A2, active site
InterPro IPR016090 Phospholipase A2 domain
InterPro IPR010711 Phospholipase A2, group XII secretory
Protein Ontology PR:000012796 group XIIA secretory phospholipase A2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory