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Pla2g12a
Gene Detail
Symbol

Name
ID
Pla2g12a
phospholipase A2, group XIIA
MGI:1913600
Synonyms
2310004B05Rik, GXII, MGC:58884, mGXII-1, Pla2g12, Rossy
Feature Type
protein coding gene
Genetic Map
Chromosome 3
59.40 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:129878622-129895821 bp, + strand
From Ensembl annotation of GRCm38

  17200 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11328  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pla2g12a

Human
homologs
Human Homolog PLA2G12A, phospholipase A2, group XIIA
NCBI Gene ID 81579
neXtProt AC  NX_Q9BZM1
Human Synonyms  GXII, PLA2G12, ROSSY
Human Chr (Location)  4q25; chr4:109709989-109730086 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pla2g12a interacts with 109 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process lipid catabolic process, lipid metabolic process, ...
Component cytoplasm, endoplasmic reticulum, ...
Function calcium ion binding, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (141)    Tissues (120)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 117
RT-PCR 24
cDNA source data(54)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(57) cDNA(54) Primer pair(3)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000027999 (Evidence)
Entrez Gene66350 (Evidence)
UniGene151951
DFCITC1580570, TC1593542, TC1593309
DoTSDT.101122564, DT.532926, DT.101122567, DT.101356174
NIA Mouse Gene IndexU003846
EC3.1.1.4
Consensus CDS ProjectCCDS17836.1, CCDS17837.1
International Mouse Knockout Project StatusPla2g12a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027999 Ensembl Gene Model | MGI Sequence Detail 17200 C57BL/6J ±  kb
transcript ENSMUST00000029629 Ensembl | MGI Sequence Detail 1541 Not Applicable 
polypeptide ENSMUSP00000029629 Ensembl | MGI Sequence Detail 192 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(7) UniProt(5)
Polymorphisms
SNPs within 2kb(285 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013090 Phospholipase A2, active site
InterPro IPR016090 Phospholipase A2 domain
InterPro IPR010711 Phospholipase A2, group XII secretory
Protein Ontology PR:000012796 group XIIA secretory phospholipase A2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory