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Lce3b Gene Detail
Summary
  • Symbol
    Lce3b
  • Name
    late cornified envelope 3B
  • Synonyms
    2310007F04Rik, Sprrl6A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913594
    NCBI Gene: 66344
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92840286-92841404 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.14 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913594
protein coding gene Chr3:92840286-92841404 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027523
protein coding gene Chr3:93408259-93409377 (+)
A/J MGP_AJ_G0027490
protein coding gene Chr3:90461456-90462686 (+)
AKR/J MGP_AKRJ_G0027455
protein coding gene Chr3:92583094-92587262 (+)
BALB/cJ MGP_BALBcJ_G0027498
protein coding gene Chr3:90272039-90273157 (+)
C3H/HeJ MGP_C3HHeJ_G0027236
protein coding gene Chr3:92801977-92803095 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027940
protein coding gene Chr3:96951699-96952817 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025289
protein coding gene Chr3:87082098-87083380 (+)
CAST/EiJ MGP_CASTEiJ_G0026684
protein coding gene Chr3:92228610-92239994 (+)
CBA/J MGP_CBAJ_G0027212
protein coding gene Chr3:100275891-100277009 (+)
DBA/2J MGP_DBA2J_G0027349
protein coding gene Chr3:89792271-89793489 (+)
FVB/NJ MGP_FVBNJ_G0027317
protein coding gene Chr3:87947865-87948983 (+)
LP/J MGP_LPJ_G0027457
protein coding gene Chr3:94618187-94619305 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027343
protein coding gene Chr3:106572686-106573804 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028000
protein coding gene Chr3:92325261-92326477 (+)
PWK/PhJ MGP_PWKPhJ_G0026413
protein coding gene Chr3:89673284-89674441 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026234
protein coding gene Chr3:90658414-90659530 (+)
WSB/EiJ MGP_WSBEiJ_G0026766
protein coding gene Chr3:92687303-92688421 (+)



Homology
more
  • Human Ortholog
    LCE3B, late cornified envelope 3B
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LCE3B, late cornified envelope 3B
  • Synonyms
    LEP14
  • Links
    NCBI Gene ID: 353143
    neXtProt AC: NX_Q5TA77
    UniProt: Q5TA77

  • Chr Location
    1q21.3; chr1:152613811-152614098 (+)  GRCh38

  • Human Ortholog
    LCE3C, late cornified envelope 3C
  • Synonyms
    LEP15, SPRL3A
  • Links
    NCBI Gene ID: 353144
    neXtProt AC: NX_Q5T5A8
    UniProt: Q5T5A8

  • Chr Location
    1q21.3; chr1:152600234-152601086 (+)  GRCh38

  • Human Ortholog
    LCE3D, late cornified envelope 3D
  • Synonyms
    LEP16, SPRL6A, SPRL6B
  • Links
    NCBI Gene ID: 84648
    neXtProt AC: NX_Q9BYE3
    UniProt: Q9BYE3

  • Chr Location
    1q21.3; chr1:152579381-152580516 (-)  GRCh38

  • Human Ortholog
    LCE3E, late cornified envelope 3E
  • Synonyms
    LEP17
  • Links
    NCBI Gene ID: 353145
    neXtProt AC: NX_Q5T5B0
    UniProt: Q5T5B0

  • Chr Location
    1q21.3; chr1:152565654-152566780 (-)  GRCh38

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Lce3b
  • Find Mice (IMSR)
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66344 NCBI Gene Model | MGI Sequence Detail 1119 C57BL/6J ±  kb
transcript NM_025501 RefSeq | MGI Sequence Detail 562 C57BL/6  
polypeptide NP_079777 RefSeq | MGI Sequence Detail 98 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR028205 Late cornified envelope protein
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Diseases 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory