Krt88 Gene Detail

Summary

• Symbol
  Krt88
• Name
  keratin 88
• Synonyms
  1700011A15Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1913572
  NCBI Gene: 66322
• Alliance
  gene page

Location & Maps

• Sequence Map
  Chr15:101447744-101453907 bp, + strand
• From Ensembl annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    6164 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, 56.90 cM, cytoband F3
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  KRT88P, keratin 88 pseudogene

• Vertebrate Orthologs
  4

• Human Ortholog
  KRT88P, keratin 88 pseudogene
  Orthology source: HGNC
• Synonyms
  HBC, KRT122P, KRTHBP3
• Links
  HGNC:30197

  NCBI Gene ID: 85348

  
  
• Chr Location
  12q13.13; chr12:52263781-52268497 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 11945
  1 mouse;1 rat;1 cattle;1 dog
  
• HCOP
  human homology predictions: KRT88P
• Gene Tree
  Krt88
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotypes from 1 allele in 1 genetic background
  27 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  1
• Radiation induced
  2
• Targeted
  3
• Genomic Mutations
  4 involving Krt88
• Incidental Mutations
  APF
• Find Mice (IMSR)
  5 strains or lines available

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• cDNA Data
  11

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Krt88 interacts with 34 markers (Mir15a, Mir31, Mir33, ...) View All

Sequences &
Gene Models

• All Sequences
  14
• RefSeq
  4
• UniProt
  1
• CCDS
  CCDS37217.1
• UniGene
  158111

• Ensembl
  ENSMUSG00000063971 (Evidence)
• NCBI Gene
  66322

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000063971	Ensembl Gene Model | MGI Sequence Detail	6164	C57BL/6J
transcript	ENSMUST00000023781	Ensembl | MGI Sequence Detail	902	Not Applicable
polypeptide	ENSMUSP00000023781	Ensembl | MGI Sequence Detail	171	Not Applicable

Polymorphisms

• SNPs within 2kb
  25 from dbSNP Build 142

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR001664 Intermediate filament protein
  IPR018039 Intermediate filament protein, conserved site
  IPR039008 Intermediate filament, rod domain

Molecular
Reagents

• All nucleic 11

  cDNA 11

  
  

  Microarray probesets 2

References

• Summaries
  All 43

  Diseases 1

  Phenotypes 27
• Earliest
  J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
• Latest
  J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9