Tmem208 MGI Mouse Gene Detail - MGI:1913570

Symbol

Tmem208
Name

transmembrane protein 208
Synonyms

1700006C06Rik, 2610030K20Rik, Hspc171, MGC:25457

Feature Type

protein coding gene
IDs

MGI:1913570
NCBI Gene: 66320
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr8:106052986-106061851 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 53.04 cM, cytoband D1
Mapping Data

2 experiments

SNPs within 2kb

255 from dbSNP Build 142
Strain Annotations

14

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913570	protein coding gene	Chr8:106052980-106062117 (+)
129S1/SvImJ	ENSMUSG00200014820	protein coding gene	Chr8:100332547-100335250 (+)
A/J	ENSMUSG00195003597	protein coding gene	Chr8:100655047-100657750 (+)
AKR/J	ENSMUSG00220014585	protein coding gene	Chr8:100788903-100791606 (+)
BALB/cJ	ENSMUSG00180022693	protein coding gene	Chr8:100660792-100663495 (+)
C3H/HeJ	ENSMUSG00175022592	protein coding gene	Chr8:100717564-100720267 (+)
C57BL/6NJ	ENSMUSG00215027929	protein coding gene	Chr8:100331906-100334609 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031476	protein coding gene	Chr8:96454182-96462881 (+)
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210032832	protein coding gene	Chr8:100645270-100647973 (+)
DBA/2J	ENSMUSG00185005336	protein coding gene	Chr8:106754060-106756763 (+)
FVB/NJ	ENSMUSG00205016613	protein coding gene	Chr8:99629539-99632242 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230032450	protein coding gene	Chr8:110434460-110437163 (+)
NOD/ShiLtJ	ENSMUSG00190021711	protein coding gene	Chr8:100784466-100787169 (+)
NZO/HlLtJ	ENSMUSG00225018419	protein coding gene	Chr8:113785027-113787730 (+)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

TMEM208, transmembrane protein 208

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TMEM208, transmembrane protein 208
Synonyms

hSND2, HSPC171, SND2
Links

HGNC:25015

NCBI Gene ID: 29100

UniProt: Q9BTX3
Chr Location

16q22.1; chr16:67227103-67229278 (+) GRCh38

MGI Vertebrate Homology

Tmem208 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TMEM208
Gene Tree

Tmem208

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Phenotype Summary

6 phenotype references

All Mutations and Alleles

14
Gene trapped

11
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

22 strains or lines available

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All GO Annotations

4
GO References

4

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

607
Tissues

9
cDNA Data

58
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tmem208

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All Sequences

53
RefSeq

14
UniProt

3
CCDS

CCDS22599.1

Ensembl

ENSMUSG00000014856 (Evidence)
NCBI Gene

66320

			Length	Strain/Species	Flank
genomic	ENSMUSG00000014856	Ensembl Gene Model \| MGI Sequence Detail	8866	C57BL/6J	± kb
transcript	ENSMUST00000098453	Ensembl \| MGI Sequence Detail	950	Not Applicable
polypeptide	ENSMUSP00000096052	Ensembl \| MGI Sequence Detail	176	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000031163 transmembrane protein 208

(term hierarchy)
InterPro Domains

IPR008506 SRP-independent targeting protein 2/TMEM208

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All nucleic 59

cDNA 58

Primer pair 1

Microarray probesets 4

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MGI:1916474

Summaries

All 33

Developmental Gene Expression 1

Gene Ontology 4

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Tmem208:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr79134	Chr8:106052986-106053043 (+)	29 bp
Tssr79135	Chr8:106053051-106053073 (+)	76 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/15/2026 MGI 6.29