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Mplkip Gene Detail
Summary
  • Symbol
    Mplkip
  • Name
    M-phase specific PLK1 intereacting protein
  • Synonyms
    2810021B07Rik, C330007M08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913558
    NCBI Gene: 66308
  • Gene Overview
    MyGene.info: MPLKIP
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:17695413-17699105 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 6.05 cM, cytoband A3.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913558
protein coding gene Chr13:17695192-17699748 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020250
protein coding gene Chr13:14750879-14754571 (+)
A/J MGP_AJ_G0020208
protein coding gene Chr13:14570952-14574644 (+)
AKR/J MGP_AKRJ_G0020182
protein coding gene Chr13:14781564-14785259 (+)
BALB/cJ MGP_BALBcJ_G0020194
protein coding gene Chr13:14531385-14535077 (+)
C3H/HeJ MGP_C3HHeJ_G0019998
protein coding gene Chr13:14863858-14867550 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020638
protein coding gene Chr13:15473663-15477307 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018245
protein coding gene Chr13:13095140-13098830 (+)
CAST/EiJ MGP_CASTEiJ_G0019532
protein coding gene Chr13:14568252-14571950 (+)
CBA/J MGP_CBAJ_G0019962
protein coding gene Chr13:15942824-15946516 (+)
DBA/2J MGP_DBA2J_G0020081
protein coding gene Chr13:14185492-14189622 (+)
FVB/NJ MGP_FVBNJ_G0020062
protein coding gene Chr13:13888494-13892186 (+)
LP/J MGP_LPJ_G0020151
protein coding gene Chr13:15029289-15032981 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020099
protein coding gene Chr13:16293187-16296879 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020666
protein coding gene Chr13:14578435-14582127 (+)
PWK/PhJ MGP_PWKPhJ_G0019295
protein coding gene Chr13:14242252-14247040 (+)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MPLKIP, M-phase specific PLK1 interacting protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MPLKIP, M-phase specific PLK1 interacting protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ABHS, C7orf11, ORF20, TTD4
  • Links
    NCBI Gene ID: 136647
    neXtProt AC: NX_Q8TAP9
    UniProt: Q8TAP9

  • Chr Location
    7p14.1; chr7:40132743-40134652 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human MPLKIP associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66308 NCBI Gene Model | MGI Sequence Detail 3693 C57BL/6J ±  kb
transcript NM_025479 RefSeq | MGI Sequence Detail 2679 C57BL/6  
polypeptide Q9D011 UniProt | EBI | MGI Sequence Detail 178 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
Other
Accession IDs
less
MGI:1924888
References
more
  • Summaries
    All 38
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:256989 King R, et al., Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma. PLoS Genet. 2018 Jan;14(1):e1007145

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory