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Pdcd5 Gene Detail
Summary
  • Symbol
    Pdcd5
  • Name
    programmed cell death 5
  • Synonyms
    2200003D22Rik, Tfar19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913538
    NCBI Gene: 56330
  • Gene Overview
    MyGene.info: PDCD5
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:35641985-35647482 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 21.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913538
protein coding gene Chr7:35641982-35647521 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032094
protein coding gene Chr7:35038117-35045419 (-)
A/J MGP_AJ_G0032074
protein coding gene Chr7:34110690-34116506 (-)
AKR/J MGP_AKRJ_G0032007
protein coding gene Chr7:34953884-34961908 (-)
BALB/cJ MGP_BALBcJ_G0032081
protein coding gene Chr7:34398997-34408307 (-)
C3H/HeJ MGP_C3HHeJ_G0031798
protein coding gene Chr7:35824491-35830137 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032558
protein coding gene Chr7:36810023-36817682 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029591
protein coding gene Chr7:34863082-34868614 (-)
CAST/EiJ MGP_CASTEiJ_G0031133
protein coding gene Chr7:27002418-27008933 (-)
CBA/J MGP_CBAJ_G0031766
protein coding gene Chr7:37924454-37930133 (-)
DBA/2J MGP_DBA2J_G0031918
protein coding gene Chr7:33955343-33960860 (-)
FVB/NJ MGP_FVBNJ_G0031871
protein coding gene Chr7:33885660-33891315 (-)
LP/J MGP_LPJ_G0031995
protein coding gene Chr7:35383017-35390656 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031911
protein coding gene Chr7:36925603-36931136 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032573
protein coding gene Chr7:34499515-34505000 (-)
PWK/PhJ MGP_PWKPhJ_G0030855
protein coding gene Chr7:27299933-27305677 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030690
protein coding gene Chr7:24061102-24066619 (-)
WSB/EiJ MGP_WSBEiJ_G0031243
protein coding gene Chr7:35041695-35048329 (-)



Homology
more
  • Human Ortholog
    PDCD5, programmed cell death 5
  • Vertebrate Orthologs
    12
  • Human Ortholog
    PDCD5, programmed cell death 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TFAR19
  • Links
    NCBI Gene ID: 9141
    neXtProt AC: NX_O14737
    UniProt: O14737

  • Chr Location
    19q13.11; chr19:32581161-32587452 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56330 NCBI Gene Model | MGI Sequence Detail 5498 C57BL/6J ±  kb
transcript NM_019746 RefSeq | MGI Sequence Detail 642 C57BL/6  
polypeptide NP_062720 RefSeq | MGI Sequence Detail 126 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138083
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:51997 Liu H, et al., TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal. Biochem Biophys Res Commun. 1999 Jan 8;254(1):203-10
  • Latest
    J:262888 Lee SH, et al., Programmed cell death 5 suppresses AKT-mediated cytoprotection of endothelium. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4672-4677

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory