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Aamdc Gene Detail
Summary
  • Symbol
    Aamdc
  • Name
    adipogenesis associated Mth938 domain containing
  • Synonyms
    1810020D17Rik, 1810037D19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913523
    NCBI Gene: 66273
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:97550331-97579497 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 53.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    258 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913523
protein coding gene Chr7:97550329-97579509 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032527
protein coding gene Chr7:100255400-100285707 (-)
A/J MGP_AJ_G0032501
protein coding gene Chr7:97765863-97796033 (-)
AKR/J MGP_AKRJ_G0032437
protein coding gene Chr7:100098718-100128893 (-)
BALB/cJ MGP_BALBcJ_G0032512
protein coding gene Chr7:97458879-97488051 (-)
C3H/HeJ MGP_C3HHeJ_G0032227
protein coding gene Chr7:100446417-100476120 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033010
protein coding gene Chr7:104158029-104188337 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030005
protein coding gene Chr7:100217653-100246838 (-)
CAST/EiJ MGP_CASTEiJ_G0031554
protein coding gene Chr7:91953418-91993520 (-)
CBA/J MGP_CBAJ_G0032194
protein coding gene Chr7:107667621-107697491 (-)
DBA/2J MGP_DBA2J_G0032346
protein coding gene Chr7:96122142-96151488 (-)
FVB/NJ MGP_FVBNJ_G0032302
protein coding gene Chr7:95912908-95942000 (-)
LP/J MGP_LPJ_G0032435
protein coding gene Chr7:101576920-101606152 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032335
protein coding gene Chr7:109204598-109236936 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033032
protein coding gene Chr7:99383772-99413013 (-)
PWK/PhJ MGP_PWKPhJ_G0031272
protein coding gene Chr7:89178399-89212730 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031115
protein coding gene Chr7:86619549-86648445 (-)
WSB/EiJ MGP_WSBEiJ_G0031671
protein coding gene Chr7:100024580-100056254 (-)



Homology
more
  • Human Ortholog
    AAMDC, adipogenesis associated Mth938 domain containing
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AAMDC, adipogenesis associated Mth938 domain containing
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C11orf67, CK067, PTD015
  • Links
    NCBI Gene ID: 28971
    neXtProt AC: NX_Q9H7C9
    UniProt: Q9H7C9

  • Chr Location
    11q14.1; chr11:77821114-77901281 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
  • All Mutations and Alleles
    48
  • Chemically induced (other)
    1
  • Gene trapped
    45
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Aamdc
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035642 Ensembl Gene Model | MGI Sequence Detail 29167 C57BL/6J ±  kb
transcript ENSMUST00000178078 Ensembl | MGI Sequence Detail 723 Not Applicable  
polypeptide ENSMUSP00000137067 Ensembl | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • InterPro Domains
    IPR034096 Mth938 domain-containing protein
    IPR036748 MTH938-like superfamily
    IPR007523 NDUFAF3/Mth938 domain-containing protein
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916422
References
more
  • Summaries
    All 48
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 25
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:181917 Ma X, et al., LOC66273 isoform 2, a novel protein highly expressed in white adipose tissue, induces adipogenesis in 3T3-L1 cells. J Nutr. 2012 Mar;142(3):448-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory