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Fam134b Gene Detail
Summary
  • Symbol
    Fam134b
  • Name
    family with sequence similarity 134, member B
  • Synonyms
    1810015C04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913520
    NCBI Gene: 66270
Location & Maps
more
  • Sequence Map
    Chr15:25843298-25973696 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      130399 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    FAM134B, family with sequence similarity 134 member B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FAM134B, family with sequence similarity 134 member B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    JK1, JK-1
  • Links
    NCBI Gene ID: 54463
    neXtProt AC: NX_Q9H6L5

  • Chr Location
    5p15.1; chr5:16472816-16617058 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human FAM134B associations

Human Disease Mouse Models
       Neuropathy, Hereditary Sensory and Autonomic, Type IIA; HSAN2A   OMIM: 201300
Neuropathy, Hereditary Sensory and Autonomic, Type IIB; HSAN2B   OMIM: 613115
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Gene trapped
    3
  • Targeted
    1
  • Genomic Mutations
    2 involving Fam134b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66270 NCBI Gene Model | MGI Sequence Detail 130399 C57BL/6J ±  kb
transcript NM_001277315 RefSeq | MGI Sequence Detail 3228 C57BL/6  
polypeptide Q8VE91 UniProt | EBI | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    617 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031111 protein FAM134B
Molecular
Reagents
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  • All nucleic 16
    cDNA 16

    Microarray probesets 4
Other
Accession IDs
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MGI:2146123
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:222922 Khaminets A, et al., Regulation of endoplasmic reticulum turnover by selective autophagy. Nature. 2015 Jun 18;522(7556):354-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory