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Eapp Gene Detail
Summary
  • Symbol
    Eapp
  • Name
    E2F-associated phosphoprotein
  • Synonyms
    1810011O16Rik, EAPP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913516
    NCBI Gene: 66266
  • Gene Overview
    MyGene.info: EAPP
Location & Maps
more
  • Sequence Map
    Chr12:54670340-54695897 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25558 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 23.46 cM, cytoband C1
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EAPP, E2F associated phosphoprotein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EAPP, E2F associated phosphoprotein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BM036, C14orf11
  • Links
    NCBI Gene ID: 55837
    neXtProt AC: NX_Q56P03

  • Chr Location
    14q13.1; chr14:34515929-34539737 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 10206
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: EAPP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Targeted
    2
  • Genomic Mutations
    1 involving Eapp
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034925 VEGA Gene Model | MGI Sequence Detail 25558 C57BL/6J ±  kb
transcript OTTMUST00000088803 VEGA | MGI Sequence Detail 4186 Not Applicable  
polypeptide OTTMUSP00000048446 VEGA | MGI Sequence Detail 281 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    93 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000006865 E2F-associated phosphoprotein
  • InterPro Domains
    IPR019370 E2F-associated phosphoprotein
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:100168 Novy M, et al., EAPP, a novel E2F binding protein that modulates E2F-dependent transcription. Mol Biol Cell. 2005 May;16(5):2181-90

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory