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Eapp
Gene Detail
 Symbol
Name
ID
Eapp
E2F-associated phosphoprotein
MGI:1913516
Synonyms 1810011O16Rik, EAPP
Feature Type protein coding gene
Genetic Map
Chromosome 12
23.46 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:54670340-54695897 bp, - strand
From VEGA annotation of GRCm38

  25558 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10206  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Eapp

Human
homologs
Human Homolog EAPP, E2F-associated phosphoprotein
NCBI Gene ID 55837
neXtProt AC  NX_Q56P03
Human Synonyms  BM036, C14orf11
Human Chr (Location)  14q13.1; chr14:34515929-34539737 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(10) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Eapp interacts with 300 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process negative regulation of transcription elongation from RNA polymerase II promoter, positive regulation of cell proliferation, ...
Component cytoplasm, Golgi apparatus, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(29)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(29) cDNA(29)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034925 (Evidence)
Ensembl Gene ModelENSMUSG00000054302 (Evidence)
Entrez Gene66266 (Evidence)
UniGene156440
DFCITC1580437, TC1596404
DoTSDT.40134493
NIA Mouse Gene IndexU033949
Consensus CDS ProjectCCDS25910.1
International Mouse Knockout Project StatusEapp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034925 VEGA Gene Model | MGI Sequence Detail 25558 C57BL/6J ±  kb
transcript OTTMUST00000088803 VEGA | MGI Sequence Detail 4186 Not Applicable 
polypeptide OTTMUSP00000048446 VEGA | MGI Sequence Detail 281 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(6) UniProt(5)
Polymorphisms SNPs within 2kb(108 from dbSNP Build 137)    SNPs within 2kb including multiple locations(116)
Protein-related
information
ResourceIDDescription
InterPro IPR019370 E2F-associated phosphoprotein
Protein Ontology PR:000006865 E2F-associated phosphoprotein
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:100168 Novy M, et al., EAPP, a novel E2F binding protein that modulates E2F-dependent transcription. Mol Biol Cell. 2005 May;16(5):2181-90
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory