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Tm4sf20 Gene Detail
Summary
  • Symbol
    Tm4sf20
  • Name
    transmembrane 4 L six family member 20
  • Synonyms
    1810018L02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913511
    NCBI Gene: 66261
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:82756649-82768456 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 42.48 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    174 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913511
protein coding gene Chr1:82756649-82768461 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016219
protein coding gene Chr1:83677746-83689557 (-)
A/J MGP_AJ_G0016202
protein coding gene Chr1:80709323-80721808 (-)
AKR/J MGP_AKRJ_G0016159
protein coding gene Chr1:82910570-82922422 (-)
BALB/cJ MGP_BALBcJ_G0016157
protein coding gene Chr1:80854118-80865931 (-)
C3H/HeJ MGP_C3HHeJ_G0015987
protein coding gene Chr1:83292849-83304661 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016610
protein coding gene Chr1:86904219-86916033 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014330
protein coding gene Chr1:75931671-75944350 (-)
CAST/EiJ MGP_CASTEiJ_G0015573
protein coding gene Chr1:82709529-82721330 (-)
CBA/J MGP_CBAJ_G0015961
protein coding gene Chr1:89696173-89708023 (-)
DBA/2J MGP_DBA2J_G0016062
protein coding gene Chr1:79999497-80011301 (-)
FVB/NJ MGP_FVBNJ_G0016065
protein coding gene Chr1:79093900-79105757 (-)
LP/J MGP_LPJ_G0016135
protein coding gene Chr1:84793865-84806283 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016085
protein coding gene Chr1:93087440-93099302 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016657
protein coding gene Chr1:83075332-83087133 (-)
PWK/PhJ MGP_PWKPhJ_G0015358
protein coding gene Chr1:79439882-79452586 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015136
protein coding gene Chr1:82271873-82283697 (-)
WSB/EiJ MGP_WSBEiJ_G0015633
protein coding gene Chr1:82875269-82887133 (-)



Homology
more
  • Human Ortholog
    TM4SF20, transmembrane 4 L six family member 20
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TM4SF20, transmembrane 4 L six family member 20
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PRO994, SLI5, TCCE518
  • Links
    NCBI Gene ID: 79853
    neXtProt AC: NX_Q53R12
    UniProt: Q53R12

  • Chr Location
    2q36.3; chr2:227362041-227379306 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human TM4SF20 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Tm4sf20
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66261 NCBI Gene Model | MGI Sequence Detail 11808 C57BL/6J ±  kb
transcript NM_025453 RefSeq | MGI Sequence Detail 1510 C57BL/6  
polypeptide Q9CQY8 UniProt | EBI | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:175542 Anderson KR, et al., The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011 Aug;138(15):3213-24

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory