Ssr2
Gene Detail

Symbol

Name
ID

Ssr2
signal sequence receptor, beta
MGI:1913506

Synonyms

TRAPbeta

Feature Type

protein coding gene

Genetic Map

Chromosome 3
38.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr3:88579583-88588420 bp, + strand From NCBI annotation of GRCm38   8838 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:2369  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: translocon-associated protein, beta subunit
Gene Tree: Ssr2

Human
homologs

Human Homolog		SSR2, signal sequence receptor, beta (translocon-associated protein beta)
NCBI Gene ID		6746
neXtProt AC		NX_P43308
Human Synonyms		TLAP, TRAPB, TRAP-BETA
Human Chr (Location)		1q21-q23; chr1:156009048-156020967 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(206) : Gene trapped(203) Targeted(3)

Interactions

Ssr2 interacts with 62 markers (Mir22, Mir23a, Mir23b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (7 annotations)

Process	biological_process
Component	endoplasmic reticulum, integral component of membrane, ...
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (5 records)

Data Summary: Results (47)    Tissues (24)    Images (17)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	43
RT-PCR	4

cDNA source data(245)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(247) cDNA(245) Primer pair(1) Other(1)
Microarray probesets(3)

Other database
links

Ensembl Gene Model	ENSMUSG00000041355 (Evidence)
Entrez Gene	66256 (Evidence)
UniGene	7091
DFCI	TC1571883
DoTS	DT.101403188, DT.495760
NIA Mouse Gene Index	U003442
Consensus CDS Project	CCDS17480.1
International Mouse Knockout Project Status	Ssr2

Sequences

Length	Strain/Species
genomic	66256	NCBI Gene Model | MGI Sequence Detail	8838	C57BL/6J
transcript	NM_025448	RefSeq | MGI Sequence Detail	1183	C57BL/6
polypeptide	Q9CPW5	UniProt | EBI | MGI Sequence Detail	183	Not Applicable

All sequences(43) RefSeq(4) UniProt(1)

Polymorphisms

SNPs within 2kb(35 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR008856	Translocon-associated protein subunit beta
Protein Ontology	PR:000015660	translocon-associated protein subunit beta

Graphical View of Protein Domain Structure

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(42)

Other
accession IDs

MGI:2139666, MGI:2139881