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Ssr2 Gene Detail
Summary
  • Symbol
    Ssr2
  • Name
    signal sequence receptor, beta
  • Synonyms
    TRAPbeta
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913506
    NCBI Gene: 66256
  • Gene Overview
    MyGene.info: SSR2
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr3:88575876-88588419 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      12544 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 38.88 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SSR2, signal sequence receptor subunit 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SSR2, signal sequence receptor subunit 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSD25, TLAP, TRAPB, TRAP-BETA
  • Links
    NCBI Gene ID: 6746
    neXtProt AC: NX_P43308
    UniProt: P43308

  • Chr Location
    1q22; chr1:156009048-156020992 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    42 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    47
  • Tissues
    24
  • cDNA Data
    245
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000052161 VEGA Gene Model | MGI Sequence Detail 12544 C57BL/6J ±  kb
    transcript OTTMUST00000131082 VEGA | MGI Sequence Detail 620 Not Applicable  
    polypeptide OTTMUSP00000070159 VEGA | MGI Sequence Detail 185 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      36 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • InterPro Domains
      IPR008856 Translocon-associated protein subunit beta
    Molecular
    Reagents
    less
    • All nucleic 247
      cDNA 245
      Primer pair 1
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2139666, MGI:2139881
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 3
      Phenotypes 18
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:261316 Perez-Garcia V, et al., Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018 Mar 22;555(7697):463-468
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/12/2018
    MGI 6.12     		The Jackson Laboratory