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Arfgap3 Gene Detail
Summary
  • Symbol
    Arfgap3
  • Name
    ADP-ribosylation factor GTPase activating protein 3
  • Synonyms
    0610009H19Rik, 1810004P07Rik, 1810035F16Rik, 9130416J18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913501
    NCBI Gene: 66251
  • Gene Overview
    MyGene.info: ARFGAP3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:83299739-83350247 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 39.40 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913501
protein coding gene Chr15:83299739-83350347 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022162
protein coding gene Chr15:83991638-84046518 (-)
A/J MGP_AJ_G0022121
protein coding gene Chr15:80916607-80969685 (-)
AKR/J MGP_AKRJ_G0022096
protein coding gene Chr15:83256115-83318754 (-)
BALB/cJ MGP_BALBcJ_G0022127
protein coding gene Chr15:81060648-81111631 (-)
C3H/HeJ MGP_C3HHeJ_G0021897
protein coding gene Chr15:83229925-83284203 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022572
protein coding gene Chr15:87229880-87286600 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020096
protein coding gene Chr15:77297437-77346143 (-)
CAST/EiJ MGP_CASTEiJ_G0021419
protein coding gene Chr15:83999567-84055180 (-)
CBA/J MGP_CBAJ_G0021864
protein coding gene Chr15:89976855-90040371 (-)
DBA/2J MGP_DBA2J_G0021991
protein coding gene Chr15:80400933-80455546 (-)
FVB/NJ MGP_FVBNJ_G0021970
protein coding gene Chr15:79447885-79497843 (-)
LP/J MGP_LPJ_G0022062
protein coding gene Chr15:84161868-84219407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021990
protein coding gene Chr15:94910118-94963230 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022587
protein coding gene Chr15:83277705-83328459 (-)
PWK/PhJ MGP_PWKPhJ_G0021160
protein coding gene Chr15:80385698-80439256 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020994
protein coding gene Chr15:82998216-83049920 (-)
WSB/EiJ MGP_WSBEiJ_G0021468
protein coding gene Chr15:83769886-83827116 (-)



Homology
more
  • Human Ortholog
    ARFGAP3, ADP ribosylation factor GTPase activating protein 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ARFGAP3, ADP ribosylation factor GTPase activating protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARFGAP1
  • Links
    NCBI Gene ID: 26286
    neXtProt AC: NX_Q9NP61
    UniProt: Q9NP61

  • Chr Location
    22q13.2; chr22:42796526-42857402 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054277 Ensembl Gene Model | MGI Sequence Detail 50509 C57BL/6J ±  kb
transcript ENSMUST00000067215 Ensembl | MGI Sequence Detail 2619 Not Applicable  
polypeptide ENSMUSP00000064893 Ensembl | MGI Sequence Detail 524 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR038508 ArfGAP domain superfamily
    IPR037278 ARFGAP/RecO-like zinc finger
    IPR001164 Arf GTPase activating protein
Molecular
Reagents
less
  • All nucleic 80
    cDNA 80

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916388, MGI:1921803, MGI:1922640
References
more
  • Summaries
    All 48
    Diseases 1
    Gene Ontology 4
    Phenotypes 22
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory