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Pno1
Gene Detail
Symbol

Name
ID
Pno1
partner of NOB1 homolog (S. cerevisiae)
MGI:1913499
Synonyms
1810003N24Rik, Emi3, expressed during mesenchymal induction 3, Imi3
Feature Type
protein coding gene
Genetic Map
Chromosome 11
9.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:17203198-17211568 bp, - strand
From VEGA annotation of GRCm38

  8371 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6961  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pno1

Human
homologs
Human Homolog PNO1, partner of NOB1 homolog (S. cerevisiae)
NCBI Gene ID 56902
neXtProt AC  NX_Q9NRX1
Human Synonyms  KHRBP1, RRP20
Human Chr (Location)  2p14; chr2:68157873-68175959 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(4) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit eombryonic lethality between E3.5 and E6.5.
 
Interactions
Pno1 interacts with 108 markers (Mir10a, Mir16-1, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process biological_process
Component nucleolus, nucleus
Function nucleic acid binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (109)    Tissues (39)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 107
RT-PCR 2
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005193 (Evidence)
Ensembl Gene ModelENSMUSG00000020116 (Evidence)
Entrez Gene66249 (Evidence)
DFCITC1575338
DoTSDT.494027
NIA Mouse Gene IndexU032536
Consensus CDS ProjectCCDS24449.1
International Mouse Knockout Project StatusPno1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005193 VEGA Gene Model | MGI Sequence Detail 8371 C57BL/6J ±  kb
transcript OTTMUST00000011607 VEGA | MGI Sequence Detail 1544 Not Applicable 
polypeptide OTTMUSP00000005395 VEGA | MGI Sequence Detail 248 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(118 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004087 K Homology domain
InterPro IPR004088 K Homology domain, type 1
Protein Ontology PR:000012939 RNA-binding protein PNO1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:191966 Wang X, et al., Pno1 tissue-specific expression and its functions related to the immune responses and proteasome activities. PLoS One. 2012;7(9):e46093
All references(38)
Other
accession IDs
MGI:1927107, MGI:2143970, MGI:2144372, MGI:2144395, MGI:2144431

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory