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Atp6v1g2 Gene Detail
Summary
  • Symbol
    Atp6v1g2
  • Name
    ATPase, H+ transporting, lysosomal V1 subunit G2
  • Synonyms
    1500002D01Rik, Atp6g2, lysosomal 13kDa, NG38, VAG2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913487
    NCBI Gene: 66237
  • Gene Overview
    MyGene.info: ATP6V1G2
Location & Maps
more
  • Sequence Map
    Chr17:35233660-35238767 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5108 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.60 cM, cytoband B2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ATP6V1G2, ATPase H+ transporting V1 subunit G2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ATP6V1G2, ATPase H+ transporting V1 subunit G2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ATP6G, ATP6G2, NG38, VMA10
  • Links
    NCBI Gene ID: 534
    neXtProt AC: NX_O95670

  • Chr Location
    6p21.3; chr6:31544451-31546848 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
  • All Mutations and Alleles
    9
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    1 involving Atp6v1g2
Mice homozygous for a knock-out allele are produced in the expected ratio.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031451 VEGA Gene Model | MGI Sequence Detail 5108 C57BL/6J ±  kb
transcript OTTMUST00000077935 VEGA | MGI Sequence Detail 1528 Not Applicable  
polypeptide OTTMUSP00000041326 VEGA | MGI Sequence Detail 118 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004490 V-type proton ATPase subunit G 2
  • InterPro Domains
    IPR005124 Vacuolar (H+)-ATPase G subunit
Molecular
Reagents
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  • All nucleic 35
    cDNA 35

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:63110 Martin AM, et al., Immunol Today. 2000;21(7):Centerfold
  • Latest
    J:224136 Kawamura N, et al., Loss of G2 subunit of vacuolar-type proton transporting ATPase leads to G1 upregulation in the brain. Sci Rep. 2015;5:14027

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory