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Atp6v1g2 Gene Detail
Summary
  • Symbol
    Atp6v1g2
  • Name
    ATPase, H+ transporting, lysosomal V1 subunit G2
  • Synonyms
    1500002D01Rik, Atp6g2, lysosomal 13kDa, NG38, VAG2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913487
    NCBI Gene: 66237
  • Gene Overview
    MyGene.info: ATP6V1G2
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35235166-35238767 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.60 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913487
protein coding gene Chr17:35233660-35238767 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023632
protein coding gene Chr17:35385128-35390235 (+)
A/J MGP_AJ_G0023591
protein coding gene Chr17:34203849-34208927 (+)
AKR/J MGP_AKRJ_G0023560
protein coding gene Chr17:34683963-34689068 (+)
BALB/cJ MGP_BALBcJ_G0023598
protein coding gene Chr17:34349339-34354417 (+)
C3H/HeJ MGP_C3HHeJ_G0023359
protein coding gene Chr17:35089352-35094457 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024037
protein coding gene Chr17:36740528-36745635 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021518
protein coding gene Chr17:31976246-31981331 (+)
CAST/EiJ MGP_CASTEiJ_G0022855
protein coding gene Chr17:35098415-35103519 (+)
CBA/J MGP_CBAJ_G0023337
protein coding gene Chr17:38242530-38247635 (+)
DBA/2J MGP_DBA2J_G0023465
protein coding gene Chr17:33531115-33536193 (+)
FVB/NJ MGP_FVBNJ_G0023432
protein coding gene Chr17:33373205-33378308 (+)
LP/J MGP_LPJ_G0023542
protein coding gene Chr17:35714470-35719577 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023454
protein coding gene Chr17:37169912-37175019 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024082
protein coding gene Chr17:34914233-34919332 (+)
PWK/PhJ MGP_PWKPhJ_G0022603
protein coding gene Chr17:32372161-32377264 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022423
protein coding gene Chr17:32923083-32928135 (+)
WSB/EiJ MGP_WSBEiJ_G0022919
protein coding gene Chr17:35043293-35048409 (+)



Homology
more
  • Human Ortholog
    ATP6V1G2, ATPase H+ transporting V1 subunit G2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ATP6V1G2, ATPase H+ transporting V1 subunit G2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATP6G, ATP6G2, NG38, VMA10
  • Links
    NCBI Gene ID: 534
    neXtProt AC: NX_O95670
    UniProt: O95670

  • Chr Location
    6p21.33; chr6:31544451-31546848 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Mice homozygous for a knock-out allele are produced in the expected ratio.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66237 NCBI Gene Model | MGI Sequence Detail 3602 C57BL/6J ±  kb
transcript NM_001347351 RefSeq | MGI Sequence Detail 1584 C57BL/6  
polypeptide Q9WTT4 UniProt | EBI | MGI Sequence Detail 118 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 36
    Other 2

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:63110 Martin AM, et al., Immunol Today. 2000;21(7):Centerfold
  • Latest
    J:224136 Kawamura N, et al., Loss of G2 subunit of vacuolar-type proton transporting ATPase leads to G1 subunit upregulation in the brain. Sci Rep. 2015 Sep 10;5:14027

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory