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Eif1ax Gene Detail
Summary
  • Symbol
    Eif1ax
  • Name
    eukaryotic translation initiation factor 1A, X-linked
  • Synonyms
    1500010B24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913485
    NCBI Gene: 66235
Location & Maps
more
  • Sequence Map
    ChrX:159372178-159389928 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17751 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    EIF1AX, eukaryotic translation initiation factor 1A, X-linked
  • Vertebrate Orthologs
    7
  • Human Ortholog
    EIF1AX, eukaryotic translation initiation factor 1A, X-linked
    Orthology source: HGNC
  • Synonyms
    eIF-1A, EIF1A, EIF1AP1, eIF-4C, EIF4C
  • Links
    NCBI Gene ID: 1964
    neXtProt AC: NX_P47813

  • Chr Location
    Xp22.12; chrX:20124518-20141848 (-)  GRCh38.p2

  • Human Ortholog
    EIF1AY, eukaryotic translation initiation factor 1A, Y-linked
    Orthology source: HomoloGene
  • Synonyms
    eIF-4C
  • Links
    NCBI Gene ID: 9086
    neXtProt AC: NX_O14602

  • Chr Location
    Yq11.223; chrY:20575711-20593154 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    22
  • Gene trapped
    19
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Eif1ax
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019437 VEGA Gene Model | MGI Sequence Detail 17751 C57BL/6J ±  kb
transcript OTTMUST00000046408 VEGA | MGI Sequence Detail 5172 Not Applicable  
polypeptide OTTMUSP00000020950 VEGA | MGI Sequence Detail 144 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    57 from dbSNP Build 137
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR012340 Nucleic acid-binding, OB-fold
    IPR006196 RNA-binding domain, S1, IF1 type
    IPR001253 Translation initiation factor 1A (eIF-1A)
    IPR018104 Translation initiation factor 1A (eIF-1A), conserved site
Molecular
Reagents
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  • All nucleic 24
    cDNA 24

    Microarray probesets 9
Other
Accession IDs
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MGI:2147882
References
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  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory