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Eif1ax Gene Detail
Summary
  • Symbol
    Eif1ax
  • Name
    eukaryotic translation initiation factor 1A, X-linked
  • Synonyms
    1500010B24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913485
    NCBI Gene: 66235
  • Gene Overview
    MyGene.info: EIF1AX
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:159372195-159385699 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 73.41 cM, cytoband F4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913485
protein coding gene ChrX:159372178-159389928 (.)
129S1/SvImJ MGP_129S1SvImJ_G0036224
protein coding gene ChrX:157266759-157285633 (+)
A/J MGP_AJ_G0036194
protein coding gene ChrX:156553842-156571904 (+)
AKR/J MGP_AKRJ_G0036122
protein coding gene ChrX:161519539-161541101 (+)
BALB/cJ MGP_BALBcJ_G0036187
protein coding gene ChrX:154627288-154647175 (+)
C3H/HeJ MGP_C3HHeJ_G0035893
protein coding gene ChrX:157661129-157679811 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036709
protein coding gene ChrX:161954892-161975404 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033531
protein coding gene ChrX:147835710-147853377 (+)
CAST/EiJ MGP_CASTEiJ_G0035182
protein coding gene ChrX:136702373-136723654 (+)
CBA/J MGP_CBAJ_G0035868
protein coding gene ChrX:166565846-166583738 (+)
DBA/2J MGP_DBA2J_G0036034
protein coding gene ChrX:155535837-155556957 (+)
FVB/NJ MGP_FVBNJ_G0035965
protein coding gene ChrX:154657456-154675162 (+)
LP/J MGP_LPJ_G0036119
protein coding gene ChrX:158433315-158451596 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035997
protein coding gene ChrX:175261297-175280284 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036750
protein coding gene ChrX:156812262-156832998 (+)
PWK/PhJ MGP_PWKPhJ_G0034880
protein coding gene ChrX:133586532-133604858 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034701
protein coding gene ChrX:137129813-137147787 (+)
WSB/EiJ MGP_WSBEiJ_G0035317
protein coding gene ChrX:154779249-154796906 (+)



Homology
more
  • Human Ortholog
    EIF1AX, eukaryotic translation initiation factor 1A X-linked
  • Vertebrate Orthologs
    7
  • Human Ortholog
    EIF1AX, eukaryotic translation initiation factor 1A X-linked
    Orthology source: HGNC
  • Synonyms
    eIF-1A, EIF1A, EIF1AP1, eIF-4C, EIF4C
  • Links
    NCBI Gene ID: 1964
    neXtProt AC: NX_P47813
    UniProt: P47813

  • Chr Location
    Xp22.12; chrX:20124518-20141848 (-)  GRCh38.p7

  • Human Ortholog
    EIF1AY, eukaryotic translation initiation factor 1A Y-linked
    Orthology source: HomoloGene
  • Synonyms
    eIF-4C
  • Links
    NCBI Gene ID: 9086
    neXtProt AC: NX_O14602
    UniProt: O14602

  • Chr Location
    Yq11.223; chrY:20575711-20593154 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66235 NCBI Gene Model | MGI Sequence Detail 13505 C57BL/6J ±  kb
transcript NM_025437 RefSeq | MGI Sequence Detail 4865 C57BL/6  
polypeptide Q8BMJ3 UniProt | EBI | MGI Sequence Detail 144 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR012340 Nucleic acid-binding, OB-fold
    IPR006196 RNA-binding domain, S1, IF1 type
    IPR001253 Translation initiation factor 1A (eIF-1A)
    IPR018104 Translation initiation factor 1A (eIF-1A), conserved site
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 9
Other
Accession IDs
less
MGI:2147882
References
more
  • Summaries
    All 30
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:46359 Blair HJ, et al., Mouse mutants carrying deletions that remove the genes mutated in Coffin-Lowry syndrome and lactic acidosis. Hum Mol Genet. 1998 Mar;7(3):549-55
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory