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Commd6 Gene Detail
Summary
  • Symbol
    Commd6
  • Name
    COMM domain containing 6
  • Synonyms
    1110059J08Rik, 1700063H17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913450
    NCBI Gene: 66200
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:101871202-101877907 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 50.90 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    360 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913450
 protein coding gene Chr14:101870417-101878122 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021622
 protein coding gene Chr14:98061354-98068275 (-)
A/J MGP_AJ_G0021580
 protein coding gene Chr14:94860550-94867470 (-)
AKR/J MGP_AKRJ_G0021556
 protein coding gene Chr14:97663209-97670128 (-)
BALB/cJ MGP_BALBcJ_G0021586
 protein coding gene Chr14:95193795-95200715 (-)
C3H/HeJ MGP_C3HHeJ_G0021364
 protein coding gene Chr14:97575339-97582259 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022026
 protein coding gene Chr14:102017807-102024727 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019566
 protein coding gene Chr14:91802767-91809805 (-)
CAST/EiJ MGP_CASTEiJ_G0020881
 protein coding gene Chr14:94898962-94905927 (-)
CBA/J MGP_CBAJ_G0021332
 protein coding gene Chr14:105767614-105774534 (-)
DBA/2J MGP_DBA2J_G0021456
 protein coding gene Chr14:94345138-94352058 (-)
FVB/NJ MGP_FVBNJ_G0021433
 protein coding gene Chr14:93335524-93342444 (-)
LP/J MGP_LPJ_G0021524
 protein coding gene Chr14:98846741-98854612 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021460
 protein coding gene Chr14:108505356-108512277 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022049
 protein coding gene Chr14:97179856-97186782 (-)
PWK/PhJ MGP_PWKPhJ_G0020624
 protein coding gene Chr14:91352512-91359521 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020462
 protein coding gene Chr14:93209986-93216920 (-)
WSB/EiJ MGP_WSBEiJ_G0020934
 protein coding gene Chr14:97833994-97840916 (-)



Homology
more
  • Human Ortholog
    COMMD6, COMM domain containing 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COMMD6, COMM domain containing 6
  • Synonyms
    Acrg
  • Links
    NCBI Gene ID: 170622
    UniProt: Q7Z4G1

  • Chr Location
    13q22.2; chr13:75525214-75549439 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    12
  • cDNA Data
    75
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66200 NCBI Gene Model | MGI Sequence Detail 6706 C57BL/6J ±  kb
transcript NM_001033132 RefSeq | MGI Sequence Detail 904 C57BL/6  
polypeptide Q3V4B5 UniProt | EBI | MGI Sequence Detail 87 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    cDNA 75

    Microarray probesets 3
Other
Accession IDs
less
MGI:1920630
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:299619 Singla A, et al., Regulation of copper homeostasis by members of the COMMD protein family. Dis Model Mech. 2020 Dec 1;:dmm045963
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory