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Pithd1 Gene Detail
Summary
  • Symbol
    Pithd1
  • Name
    PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
  • Synonyms
    1110049F12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913443
    NCBI Gene: 66193
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:135975602-135987244 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 68.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913443
protein coding gene Chr4:135975460-135987264 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028957
protein coding gene Chr4:138470423-138483552 (-)
A/J MGP_AJ_G0028916
protein coding gene Chr4:132593139-132604478 (-)
AKR/J MGP_AKRJ_G0028868
protein coding gene Chr4:136423188-136439464 (-)
BALB/cJ MGP_BALBcJ_G0028940
protein coding gene Chr4:133263786-133276453 (-)
C3H/HeJ MGP_C3HHeJ_G0028654
protein coding gene Chr4:136703380-136715894 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029381
protein coding gene Chr4:143379061-143393810 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026652
protein coding gene Chr4:125646058-125656950 (-)
CAST/EiJ MGP_CASTEiJ_G0028086
protein coding gene Chr4:134842361-134856024 (-)
CBA/J MGP_CBAJ_G0028619
protein coding gene Chr4:147324220-147339216 (-)
DBA/2J MGP_DBA2J_G0028768
protein coding gene Chr4:133025741-133037263 (-)
FVB/NJ MGP_FVBNJ_G0028735
protein coding gene Chr4:131944973-131958457 (-)
LP/J MGP_LPJ_G0028867
protein coding gene Chr4:138568797-138582380 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028761
protein coding gene Chr4:151599036-151610032 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029419
protein coding gene Chr4:136875498-136887585 (-)
PWK/PhJ MGP_PWKPhJ_G0027806
protein coding gene Chr4:129792686-129804267 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027632
protein coding gene Chr4:132692850-132704306 (-)
WSB/EiJ MGP_WSBEiJ_G0028164
protein coding gene Chr4:137052071-137064511 (-)



Homology
more
  • Human Ortholog
    PITHD1, PITH domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PITHD1, PITH domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf128, HT014, TXNL1CL
  • Links
    NCBI Gene ID: 57095
    neXtProt AC: NX_Q9GZP4
    UniProt: Q9GZP4

  • Chr Location
    1p36.11; chr1:23778386-23788232 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    3 involving Pithd1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66193 NCBI Gene Model | MGI Sequence Detail 11643 C57BL/6J ±  kb
transcript NM_025411 RefSeq | MGI Sequence Detail 1554 C57BL/6  
polypeptide Q8BWR2 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 79
    cDNA 79

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140127
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory