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Ier3ip1 Gene Detail
Summary
  • Symbol
    Ier3ip1
  • Name
    immediate early response 3 interacting protein 1
  • Synonyms
    1110057H19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913441
    NCBI Gene: 66191
  • Gene Overview
    MyGene.info: IER3IP1
Location & Maps
more
  • Sequence Map
    Chr18:76930017-76941605 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11589 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    IER3IP1, immediate early response 3 interacting protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    IER3IP1, immediate early response 3 interacting protein 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HSPC039, MEDS, PRO2309
  • Links
    NCBI Gene ID: 51124
    neXtProt AC: NX_Q9Y5U9

  • Chr Location
    18q12; chr18:47155019-47176374 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human IER3IP1 associations

Human Disease Mouse Models
       Microcephaly, Epilepsy, and Diabetes Syndrome; MEDS   OMIM: 614231
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Gene trapped
    1
  • Targeted
    1
  • Transposon induced
    1
  • Genomic Mutations
    1 involving Ier3ip1
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033485 VEGA Gene Model | MGI Sequence Detail 11589 C57BL/6J ±  kb
transcript OTTMUST00000084179 VEGA | MGI Sequence Detail 1395 Not Applicable  
polypeptide OTTMUSP00000045338 VEGA | MGI Sequence Detail 82 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    16 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008898 immediate early response 3-interacting protein 1
  • InterPro Domains
    IPR013880 Yos1-like
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
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MGI:2145319, MGI:2145320, MGI:2147249, MGI:2147332
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:178818 Wang B, et al., Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct;138(20):4487-97

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory