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Nop10 Gene Detail
Summary
  • Symbol
    Nop10
  • Name
    NOP10 ribonucleoprotein
  • Synonyms
    1110036B12Rik, H/ACA small nucleolar RNPs, Nola3, NOP10P
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913431
    NCBI Gene: 66181
Location & Maps
more
  • Sequence Map
    Chr2:112261926-112263269 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1344 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 56.99 cM, cytoband E4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NOP10, NOP10 ribonucleoprotein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    NOP10, NOP10 ribonucleoprotein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DKCB1, NOLA3, NOP10P
  • Links
    NCBI Gene ID: 55505
    neXtProt AC: NX_Q9NPE3

  • Chr Location
    15q14; chr15:34341716-34343161 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human NOP10 associations

Human Disease Mouse Models
       Dyskeratosis Congenita, Autosomal Recessive 1; DKCB1   OMIM: 224230
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Gene trapped
    9
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Nop10
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015143 VEGA Gene Model | MGI Sequence Detail 1344 C57BL/6J ±  kb
transcript OTTMUST00000035925 VEGA | MGI Sequence Detail 1109 Not Applicable  
polypeptide OTTMUSP00000016126 VEGA | MGI Sequence Detail 64 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 86
    cDNA 86

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:199000 Kappei D, et al., HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. EMBO J. 2013 Jun 12;32(12):1681-701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory