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Nop10 Gene Detail
Summary
  • Symbol
    Nop10
  • Name
    NOP10 ribonucleoprotein
  • Synonyms
    1110036B12Rik, H/ACA small nucleolar RNPs, Nola3, NOP10P
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913431
    NCBI Gene: 66181
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:112092271-112093243 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 56.99 cM, cytoband E4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913431
protein coding gene Chr2:112092271-112093614 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026286
protein coding gene Chr2:114706285-114707630 (+)
A/J MGP_AJ_G0026247
protein coding gene Chr2:110006446-110007791 (+)
AKR/J MGP_AKRJ_G0026226
protein coding gene Chr2:113097032-113098377 (+)
BALB/cJ MGP_BALBcJ_G0026260
protein coding gene Chr2:110274027-110275372 (+)
C3H/HeJ MGP_C3HHeJ_G0026005
protein coding gene Chr2:113490475-113491821 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026707
protein coding gene Chr2:118509085-118510428 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024087
protein coding gene Chr2:105239508-105240874 (+)
CAST/EiJ MGP_CASTEiJ_G0025466
protein coding gene Chr2:113682042-113683385 (-)
CBA/J MGP_CBAJ_G0025982
protein coding gene Chr2:122639974-122641319 (+)
DBA/2J MGP_DBA2J_G0026121
protein coding gene Chr2:109462402-109463747 (+)
FVB/NJ MGP_FVBNJ_G0026083
protein coding gene Chr2:108350035-108351380 (+)
LP/J MGP_LPJ_G0026222
protein coding gene Chr2:114990654-114991999 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026102
protein coding gene Chr2:127042825-127044170 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026762
protein coding gene Chr2:113163925-113165270 (+)
PWK/PhJ MGP_PWKPhJ_G0025204
protein coding gene Chr2:108971136-108972481 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025003
protein coding gene Chr2:112352602-112355998 (+)
WSB/EiJ MGP_WSBEiJ_G0025537
protein coding gene Chr2:113972743-113974086 (+)



Homology
more
  • Human Ortholog
    NOP10, NOP10 ribonucleoprotein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NOP10, NOP10 ribonucleoprotein
  • Synonyms
    DKCB1, NOLA3, NOP10P
  • Links
    NCBI Gene ID: 55505
    neXtProt AC: NX_Q9NPE3
    UniProt: Q9NPE3

  • Chr Location
    15q14; chr15:34341716-34343161 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human NOP10 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66181 NCBI Gene Model | MGI Sequence Detail 973 C57BL/6J ±  kb
    transcript NM_025403 RefSeq | MGI Sequence Detail 738 C57BL/6  
    polypeptide Q9CQS2 UniProt | EBI | MGI Sequence Detail 64 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000011321 H/ACA ribonucleoprotein complex subunit 3
    • InterPro Domains
      IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10
      IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily
    Molecular
    Reagents
    less
    • All nucleic 87
      cDNA 87

      Microarray probesets 4
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/22/2022
    MGI 6.21
    The Jackson Laboratory