About   Help   FAQ
Necap2 Gene Detail
Summary
  • Symbol
    Necap2
  • Name
    NECAP endocytosis associated 2
  • Synonyms
    1110005F07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913397
    NCBI Gene: 66147
  • Gene Overview
    MyGene.info: NECAP2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:141066512-141078357 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 73.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    175 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913397
protein coding gene Chr4:141066512-141078358 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029037
protein coding gene Chr4:144073242-144088384 (-)
A/J MGP_AJ_G0028996
protein coding gene Chr4:137826788-137839706 (-)
AKR/J MGP_AKRJ_G0028948
protein coding gene Chr4:141797248-141809086 (-)
BALB/cJ MGP_BALBcJ_G0029020
protein coding gene Chr4:138516301-138528155 (-)
C3H/HeJ MGP_C3HHeJ_G0028734
protein coding gene Chr4:142183585-142196408 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029461
protein coding gene Chr4:149120298-149134957 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026732
protein coding gene Chr4:130743406-130755736 (-)
CAST/EiJ MGP_CASTEiJ_G0028166
protein coding gene Chr4:140435950-140447912 (-)
CBA/J MGP_CBAJ_G0028698
protein coding gene Chr4:153412550-153430072 (-)
DBA/2J MGP_DBA2J_G0028848
protein coding gene Chr4:138222832-138235070 (-)
FVB/NJ MGP_FVBNJ_G0028815
protein coding gene Chr4:137329314-137342359 (-)
LP/J MGP_LPJ_G0028947
protein coding gene Chr4:144096325-144108175 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028841
protein coding gene Chr4:157272690-157284549 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029499
protein coding gene Chr4:142324612-142336471 (-)
PWK/PhJ MGP_PWKPhJ_G0027887
protein coding gene Chr4:135106123-135118596 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027712
protein coding gene Chr4:138151992-138163982 (-)
WSB/EiJ MGP_WSBEiJ_G0028244
protein coding gene Chr4:142610797-142622630 (-)



Homology
more
  • Human Ortholog
    NECAP2, NECAP endocytosis associated 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NECAP2, NECAP endocytosis associated 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55707
    neXtProt AC: NX_Q9NVZ3
    UniProt: Q9NVZ3

  • Chr Location
    1p36.13; chr1:16440672-16460090 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9168
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NECAP2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Gene trapped
    3
  • Targeted
    3
  • Genomic Mutations
    3 involving Necap2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028923 Ensembl Gene Model | MGI Sequence Detail 11846 C57BL/6J ±  kb
transcript ENSMUST00000030760 Ensembl | MGI Sequence Detail 1906 Not Applicable  
polypeptide ENSMUSP00000030760 Ensembl | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 140
    cDNA 140

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140143, MGI:2140671
References
more
  • Summaries
    All 34
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory