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Eef1e1
Gene Detail
 Symbol
Name
ID
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
MGI:1913393
Synonyms 1110003A02Rik
Feature Type protein coding gene
Genetic Map
Chromosome 13
18.38 cM, cytoband A5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:38645698-38659028 bp, - strand
From Ensembl annotation of GRCm38

  13331 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3161  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Eef1e1

Human
homologs
Human Homolog EEF1E1, eukaryotic translation elongation factor 1 epsilon 1
NCBI Gene ID 9521
neXtProt AC  NX_O43324
Human Synonyms  AIMP3, P18
Human Chr (Location)  6p24.3; chr6:8073360-8102595 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(17)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trap allele display early embryonic lethality while heterozygous mice exhibit prenatal semi-lethality and a significantly increased incidence of spontaneous tumorigenesis after 15 months of age.
 
Interactions
Eef1e1 interacts with 76 markers (Mir7-1, Mir23a, Mir23b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process DNA repair, embryo development, ...
Component aminoacyl-tRNA synthetase multienzyme complex, cytoplasm, ...
Function protein binding, translation elongation factor activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (42)    Tissues (29)    Images (13)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 42
cDNA source data(44)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(44) cDNA(44)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000001707 (Evidence)
Entrez Gene66143 (Evidence)
UniGene490319
DFCITC1578294
DoTSDT.110968228, DT.492229, DT.91587252
NIA Mouse Gene IndexU034701
Consensus CDS ProjectCCDS26465.1
International Mouse Knockout Project StatusEef1e1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001707 Ensembl Gene Model | MGI Sequence Detail 13331 C57BL/6J ±  kb
transcript ENSMUST00000001757 Ensembl | MGI Sequence Detail 1032 Not Applicable 
polypeptide ENSMUSP00000001757 Ensembl | MGI Sequence Detail 174 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(104 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004046 Glutathione S-transferase, C-terminal
InterPro IPR010987 Glutathione S-transferase, C-terminal-like
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000006907 eukaryotic translation elongation factor 1 epsilon-1
References (Earliest) J:113818 Quevillon S, et al., The p18 component of the multisynthetase complex shares a protein motif with the beta and gamma subunits of eukaryotic elongation factor 1. FEBS Lett. 1996 Oct 14;395(1):63-7
(Latest) J:155773 Tkatchenko TV, et al., Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Physiol Genomics. 2009 Nov 6;39(3):160-8
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory