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Cox7b
Gene Detail
 Symbol
Name
ID
Cox7b
cytochrome c oxidase subunit VIIb
MGI:1913392
Synonyms 1110004F07Rik
Feature Type protein coding gene
Genetic Map
Chromosome X
47.36 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:106015700-106022450 bp, + strand
From VEGA annotation of GRCm38

  6751 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1406  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle

Protein SuperFamily: cytochrome-c oxidase chain VIIb
Gene Tree: Cox7b

Human
homologs
Human Homolog COX7B, cytochrome c oxidase subunit VIIb
NCBI Gene ID 1349
neXtProt AC  NX_P24311
Human Synonyms  APLCC
Human Chr (Location)  Xq21.1; chrX:77899464-77905384 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human COX7B
Alleles
and
phenotypes
All alleles(71) : Gene trapped(71)
 
Male chimeras hemizygous for a gene trapped allele appear normal at E6.5. However, no embryos fully derived from mutant ES cells can be generated.
 
Phenotype Images(3)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process central nervous system development
Component integral component of membrane, membrane, ...
Function cytochrome-c oxidase activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (103)    Tissues (103)    Images (14)
Theiler Stages: 3, 4, 5, 11, 13, 22
Assay TypeResults
RNA in situ 96
RT-PCR 7
cDNA source data(224)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(225) cDNA(224) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000018281 (Evidence)
Ensembl Gene ModelENSMUSG00000031231 (Evidence)
Entrez Gene66142 (Evidence)
UniGene197728
DFCITC1572088
DoTSDT.537147, DT.94206643
NIA Mouse Gene IndexU020123, U081079
Consensus CDS ProjectCCDS41096.1
International Mouse Knockout Project StatusCox7b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018281 VEGA Gene Model | MGI Sequence Detail 6751 C57BL/6J ±  kb
transcript OTTMUST00000044174 VEGA | MGI Sequence Detail 1001 Not Applicable 
polypeptide OTTMUSP00000019859 VEGA | MGI Sequence Detail 80 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(67 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008433 Cytochrome C oxidase, subunit VIIB
InterPro IPR023272 Cytochrome C oxidase, subunit VIIB, domain
Protein Ontology PR:000005789 cytochrome c oxidase subunit 7B, mitochondrial
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(39)
Other
accession IDs
MGI:2138693

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory