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Cox7b
Gene Detail
Symbol

Name
ID
Cox7b
cytochrome c oxidase subunit VIIb
MGI:1913392
Synonyms
1110004F07Rik
Feature Type
protein coding gene
Genetic Map
Chromosome X
47.36 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:106015700-106022450 bp, + strand
From VEGA annotation of GRCm38

  6751 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1406  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 western clawed frog

Protein SuperFamily: cytochrome-c oxidase chain VIIb
Gene Tree: Cox7b

Human
homologs
Human Homolog COX7B, cytochrome c oxidase subunit VIIb
NCBI Gene ID 1349
neXtProt AC  NX_P24311
Human Synonyms  APLCC
Human Chr (Location)  Xq21.1; chrX:77899464-77905384 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human COX7B
Mutations,
alleles, and
phenotypes
All mutations/alleles(71) : Gene trapped(71)
Incidental mutations (data from APF )
 
Male chimeras hemizygous for a gene trapped allele appear normal at E6.5. However, no embryos fully derived from mutant ES cells can be generated.
 
Phenotype Images(3)
Interactions
Cox7b interacts with 92 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process central nervous system development
Component integral component of membrane, membrane, ...
Function cytochrome-c oxidase activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (99)    Tissues (99)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 96
RT-PCR 3
cDNA source data(224)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(225) cDNA(224) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000018281 (Evidence)
Ensembl Gene ModelENSMUSG00000031231 (Evidence)
Entrez Gene66142 (Evidence)
UniGene197728
DFCITC1572088
DoTSDT.94206643, DT.537147
NIA Mouse Gene IndexU081079, U020123
Consensus CDS ProjectCCDS41096.1
International Mouse Knockout Project StatusCox7b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018281 VEGA Gene Model | MGI Sequence Detail 6751 C57BL/6J ±  kb
transcript OTTMUST00000044174 VEGA | MGI Sequence Detail 1001 Not Applicable 
polypeptide OTTMUSP00000019859 VEGA | MGI Sequence Detail 80 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(67 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008433 Cytochrome C oxidase, subunit VIIB
InterPro IPR023272 Cytochrome C oxidase, subunit VIIB, domain
Protein Ontology PR:000005789 cytochrome c oxidase subunit 7B, mitochondrial
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(40)
Other
accession IDs
MGI:2138693

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory