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Fkbp11
Gene Detail
Symbol

Name
ID
Fkbp11
FK506 binding protein 11
MGI:1913370
Synonyms
1110002O23Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 15
54.65 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:98724373-98728198 bp, - strand
From Ensembl annotation of GRCm38

  3826 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9581  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FKBP11
Gene Tree: Fkbp11

Human
homologs
FKBP11, FK506 binding protein 11, 19 kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51303
neXtProt AC: NX_Q9NYL4

Human Synonyms: FKBP19

Human Chr (Location): 12q13.12; chr12:48921959-48925547 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(11) Radiation induced(1) Targeted(1)
Genomic Mutations involving Fkbp11 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions of this gene display increased antibody response to antibody challenge and increased inflammatory responses. Measurements of bone density are also increased.
 
Phenotype Images(2)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process chaperone-mediated protein folding, protein folding, ...
Component cytoplasm, endoplasmic reticulum membrane, ...
Function FK506 binding, isomerase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (141)    Tissues (17)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 141
cDNA source data(51)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) cDNA(51)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000003355 (Evidence)
Entrez Gene 66120 (Evidence)
UniGene 30729
DFCI TC1593595, TC1579444, TC1596505
DoTS DT.91431044, DT.91325370, DT.489818
NIA Mouse Gene Index U036627
EC 5.2.1.8
Consensus CDS Project CCDS27803.1
International Mouse Phenotyping Consortium Status Fkbp11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003355 Ensembl Gene Model | MGI Sequence Detail 3826 C57BL/6J ±  kb
transcript ENSMUST00000003445 Ensembl | MGI Sequence Detail 731 Not Applicable 
polypeptide ENSMUSP00000003445 Ensembl | MGI Sequence Detail 201 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(50 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
InterPro IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
Protein Ontology PR:000007533 peptidyl-prolyl cis-trans isomerase FKBP11
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory