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Fkbp11 Gene Detail
Summary
  • Symbol
    Fkbp11
  • Name
    FK506 binding protein 11
  • Synonyms
    1110002O23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913370
    NCBI Gene: 66120
Location & Maps
more
  • Sequence Map
    Chr15:98724373-98728198 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3826 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 54.65 cM, cytoband F2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FKBP11, FK506 binding protein 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FKBP11, FK506 binding protein 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FKBP19
  • Links
    NCBI Gene ID: 51303
    neXtProt AC: NX_Q9NYL4
    UniProt: Q9NYL4

  • Chr Location
    12q13.12; chr12:48921959-48925547 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions of this gene display increased antibody response to antibody challenge and increased inflammatory responses. Measurements of bone density are also increased.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003355 Ensembl Gene Model | MGI Sequence Detail 3826 C57BL/6J ±  kb
transcript ENSMUST00000003445 Ensembl | MGI Sequence Detail 731 Not Applicable  
polypeptide ENSMUSP00000003445 Ensembl | MGI Sequence Detail 201 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    50 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    cDNA 51

    Microarray probesets 6
References
more
  • Summaries
    All 47
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 26
  • Earliest
    J:13437 Bangham JW, Hairy ears, Eh. Mouse News Lett. 1965;33:68
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory