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Fkbp11 Gene Detail
Summary
  • Symbol
    Fkbp11
  • Name
    FK506 binding protein 11
  • Synonyms
    1110002O23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913370
    NCBI Gene: 66120
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:98724366-98728198 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3833 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 54.65 cM, cytoband F2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FKBP11, FK506 binding protein 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FKBP11, FK506 binding protein 11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FKBP19
  • Links
    NCBI Gene ID: 51303
    neXtProt AC: NX_Q9NYL4
    UniProt: Q9NYL4

  • Chr Location
    12q13.12; chr12:48921959-48925547 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions of this gene display increased antibody response to antibody challenge and increased inflammatory responses. Measurements of bone density are also increased.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66120 NCBI Gene Model | MGI Sequence Detail 3833 C57BL/6J ±  kb
    transcript NM_024169 RefSeq | MGI Sequence Detail 736 C57BL/6  
    polypeptide Q9D1M7 UniProt | EBI | MGI Sequence Detail 201 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      50 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 53
      cDNA 53

      Microarray probesets 6
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 2
      Phenotypes 26
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    09/11/2018
    MGI 6.12
    The Jackson Laboratory