Fkbp11
Gene Detail

Symbol Name ID

Fkbp11 FK506 binding protein 11 MGI:1913370

Synonyms

1110002O23Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 15

54.65 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr15:98724373-98728198 bp, - strand From Ensembl annotation of GRCm38   3826 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9581  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Fkbp11

Human homologs

Human Homolog		FKBP11, FK506 binding protein 11, 19 kDa
NCBI Gene ID		51303
neXtProt AC		NX_Q9NYL4
Human Synonyms		FKBP19
Human Chr (Location)		12q13.12; chr12:48921959-48925547 (-)  GRCh38

Mutations, alleles, and phenotypes

All mutations/alleles(13) : Gene trapped(11) Radiation induced(1) Targeted(1)
Genomic Mutations involving Fkbp11 (1)
Incidental mutations (data from Mutagenetix , APF )
 

Mice homozygous for disruptions of this gene display increased antibody response to antibody challenge and increased inflammatory responses. Measurements of bone density are also increased.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	chaperone-mediated protein folding, protein folding, ...
Component	endoplasmic reticulum membrane, integral component of membrane, ...
Function	FK506 binding, isomerase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)

Data Summary: Results (141)    Tissues (17)    Images (25)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	141

cDNA source data(51)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular reagents

All nucleic(51) cDNA(51)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000003355 (Evidence)
Entrez Gene	66120 (Evidence)
UniGene	30729
DFCI	TC1579444, TC1593595, TC1596505
DoTS	DT.489818, DT.91325370, DT.91431044
NIA Mouse Gene Index	U036627
EC	5.2.1.8
Consensus CDS Project	CCDS27803.1
International Mouse Knockout Project Status	Fkbp11

Sequences

Length	Strain/Species
genomic	ENSMUSG00000003355	Ensembl Gene Model | MGI Sequence Detail	3826	C57BL/6J
transcript	ENSMUST00000003445	Ensembl | MGI Sequence Detail	731	Not Applicable
polypeptide	ENSMUSP00000003445	Ensembl | MGI Sequence Detail	201	Not Applicable

All sequences(26) RefSeq(4) UniProt(1)

Polymorphisms

SNPs within 2kb(50 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR023566	Peptidyl-prolyl cis-trans isomerase, FKBP-type
InterPro	IPR001179	Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
Protein Ontology	PR:000007533	peptidyl-prolyl cis-trans isomerase FKBP11

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(31)